ArticleSystematic reviews2015
Faster title and abstract screening? Evaluating Abstrackr, a semi-automated online screening program for systematic reviewers.
Article in Systematic reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 27 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
94 citing papers in PubMed, 27 syntheses or guidelines pooled it.
- Pre-diagnostic circulating untargeted metabolomics and risk of overall and clinically significant prostate cancer: a systematic review and meta-analysis.British journal of cancer · 2026Pooled it
- A comparative study of screening performance between abstrackr and GPT models: Systematic review and contextual analysis.BMC medical informatics and decision making · 2025Pooled it
- Systematic review of AI/ML applications in multi-domain robotic rehabilitation: trends, gaps, and future directions.Journal of neuroengineering and rehabilitation · 2025Pooled it
- Effects of Varying Protein Amounts and Types on Diet-Induced Thermogenesis: A Systematic Review and Meta-Analysis.Advances in nutrition (Bethesda, Md.) · 2024Pooled it
- Leaking in Intimate Partner Homicide: A Systematic Review.Trauma, violence & abuse · 2024Pooled it
- Systematic Review of Gaming and Neuropsychological Assessment of Social Cognition.Neuropsychology review · 2024Pooled it
- Broccoli Consumption and Risk of Cancer: An Updated Systematic Review and Meta-Analysis of Observational Studies.Nutrients · 2024Pooled it
- Assets and depression in U.S. adults during the COVID-19 pandemic: a systematic review.Social psychiatry and psychiatric epidemiology · 2024Pooled it
- Meta-analysis shows no consistent evidence for senescence in ejaculate traits across animals.Nature communications · 2024Pooled it
- Interprofessional collaboration in primary care: what effect on patient health? A systematic literature review.BMC primary care · 2023Pooled it
- Characterizing Interoceptive Differences in Autism: A Systematic Review and Meta-analysis of Case-control Studies.Journal of autism and developmental disorders · 2023Pooled it
- The prevalence and risk factors of screen-based disordered eating among university students: a global systematic review, meta-analysis, and meta-regression.Eating and weight disorders : EWD · 2022Pooled it
- Economic evaluations of mammography to screen for breast cancer in low- and middle-income countries: A systematic review.Journal of global health · 2022Pooled it
- Abstract screening using the automated tool Rayyan: results of effectiveness in three diagnostic test accuracy systematic reviews.BMC medical research methodology · 2022Pooled it
- Emergent effects of global change on consumption depend on consumers and their resources in marine systems.Proceedings of the National Academy of Sciences of the United States of America · 2022Pooled it
- Food insecurity, type 2 diabetes, and hyperglycaemia: A systematic review and meta-analysis.Endocrinology, diabetes & metabolism · 2022Pooled it
- Exclusive Maternal Milk Compared With Exclusive Formula on Growth and Health Outcomes in Very-Low-Birthweight Preterm Infants: Phase II of the Pre-B Project and an Evidence Analysis Center Systematic Review.Frontiers in pediatrics · 2021Pooled it
- Deep Neural Network for Reducing the Screening Workload in Systematic Reviews for Clinical Guidelines: Algorithm Validation Study.Journal of medical Internet research · 2020Pooled it
- Burden of carbapenem non-susceptible infections in high-risk patients: systematic literature review and meta-analysis.Antimicrobial resistance and infection control · 2020Pooled it
- Taxation of the fat content of foods for reducing their consumption and preventing obesity or other adverse health outcomes.The Cochrane database of systematic reviews · 2020Pooled it
34 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCitation screening is time consuming and inefficient. We sought to evaluate the performance of Abstrackr, a semi-automated online tool for predictive title and abstract screening.
methodsFour systematic reviews (aHUS, dietary fibre, ECHO, rituximab) were used to evaluate Abstrackr. Citations from electronic searches of biomedical databases were imported into Abstrackr, and titles and abstracts were screened and included or excluded according to the entry criteria. This process was continued until Abstrackr predicted and classified the remaining unscreened citations as relevant or irrelevant. These classification predictions were checked for accuracy against the original review decisions. Sensitivity analyses were performed to assess the effects of including case reports in the aHUS dataset whilst screening and the effects of using larger imbalanced datasets with the ECHO dataset. The performance of Abstrackr was calculated according to the number of relevant studies missed, the workload saving, the false negative rate, and the precision of the algorithm to correctly predict relevant studies for inclusion, i.e. further full text inspection.
resultsOf the unscreened citations, Abstrackr's prediction algorithm correctly identified all relevant citations for the rituximab and dietary fibre reviews. However, one relevant citation in both the aHUS and ECHO reviews was incorrectly predicted as not relevant. The workload saving achieved with Abstrackr varied depending on the complexity and size of the reviews (9 % rituximab, 40 % dietary fibre, 67 % aHUS, and 57 % ECHO). The proportion of citations predicted as relevant, and therefore, warranting further full text inspection (i.e. the precision of the prediction) ranged from 16 % (aHUS) to 45 % (rituximab) and was affected by the complexity of the reviews. The false negative rate ranged from 2.4 to 21.7 %. Sensitivity analysis performed on the aHUS dataset increased the precision from 16 to 25 % and increased the workload saving by 10 % but increased the number of relevant studies missed. Sensitivity analysis performed with the larger ECHO dataset increased the workload saving (80 %) but reduced the precision (6.8 %) and increased the number of missed citations.
conclusionsSemi-automated title and abstract screening with Abstrackr has the potential to save time and reduce research waste.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.