Evidence map›Paper›PMID 26073559›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2015

Asymmetric Isothiourea-Catalysed Formal [3+2] Cycloadditions of Ammonium Enolates with Oxaziridines.

Siobhan R Smith, Charlene Fallan, James E Taylor, Ross McLennan, David S B Daniels, Louis C Morrill, Alexandra M Z Slawin, Andrew D Smith

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Generation and Reactivity of C(1)-Ammonium Enolates by Using Isothiourea Catalysis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Siobhan R SmithEaStCHEM, School of Chemistry, University of St Andrews, North Haugh, St Andrews, KY16 9ST (UK).
Charlene FallanEaStCHEM, School of Chemistry, University of St Andrews, North Haugh, St Andrews, KY16 9ST (UK).
James E TaylorEaStCHEM, School of Chemistry, University of St Andrews, North Haugh, St Andrews, KY16 9ST (UK).
Ross McLennanEaStCHEM, School of Chemistry, University of St Andrews, North Haugh, St Andrews, KY16 9ST (UK).
David S B DanielsEaStCHEM, School of Chemistry, University of St Andrews, North Haugh, St Andrews, KY16 9ST (UK).
Louis C MorrillEaStCHEM, School of Chemistry, University of St Andrews, North Haugh, St Andrews, KY16 9ST (UK).
Alexandra M Z SlawinEaStCHEM, School of Chemistry, University of St Andrews, North Haugh, St Andrews, KY16 9ST (UK).
Andrew D SmithEaStCHEM, School of Chemistry, University of St Andrews, North Haugh, St Andrews, KY16 9ST (UK). ads10@st.andrews.ac.uk.

Funding

European Research Council 279850
6 · The paper itself

Abstract

A highly enantioselective Lewis base-catalysed formal [3+2] cycloaddition of ammonium enolates and oxaziridines to give stereodefined oxazolidin-4-ones in high yield is described. Employing an enantioenriched oxaziridine in this process leads to a matched/mis-matched effect with the isothiourea catalyst and allowed the synthesis of either syn- or anti-stereodefined oxazolidin-4-ones in high d.r., yield and ee. Additionally, the oxazolidin-4-one products have been derivatised to afford functionalised enantioenriched building blocks.

Indexed as

asymmetric synthesisheterocyclesLewis baseorganocatalysisoxaziridines

Identifiers

PMID26073559
PMCPMC4531819

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.