Evidence map›Paper›PMID 26073177›Full record

ArticleBMC microbiology2015

In vitro antimicrobial susceptibility testing of human Brucella melitensis isolates from Qatar between 2014 - 2015.

Anand Deshmukh, Ferry Hagen, Ola Al Sharabasi, Mariamma Abraham, Godwin Wilson, Sanjay Doiphode, Muna Al Maslamani, Jacques F Meis

Abstract read
In one paragraph

Article in BMC microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Prevalence of Brucella melitensis and Brucella abortus aminoglycoside-resistant isolates: a systematic review and meta-analysis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Pooled it
  3. Veterinary medicine international · 2026
    Review
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  9. Adaptation ofMicroorganisms · 2022
    Article
  10. Pathogenicity and Its Implications in Taxonomy: ThePathogens (Basel, Switzerland) · 2022
    Review
  11. Article
  12. Whole-genome sequencing of roughEmerging microbes & infections · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anand DeshmukhMicrobiology Division, Hamad General Hospital, Doha, Qatar. adeshmukh@hamad.qa.
Ferry HagenDepartment of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands. F.Hagen@cwz.nl.
Ola Al SharabasiMicrobiology Division, Hamad General Hospital, Doha, Qatar. oalsharabasi@hmc.org.qa.
Mariamma AbrahamMicrobiology Division, Hamad General Hospital, Doha, Qatar. MABRAHAM2@hmc.org.qa.
Godwin WilsonMicrobiology Division, Al Khor Hospital, Doha, Qatar. gwilson@hmc.org.qa.
Sanjay DoiphodeMicrobiology Division, Hamad General Hospital, Doha, Qatar. sdoiphode@hmc.org.qa.
Muna Al MaslamaniDepartment of Infectious Diseases, Hamad General Hospital, Doha, Qatar. malmaslamani@hmc.org.qa.
Jacques F MeisDepartment of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands. jacques.meis@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBrucellosis is one of the most common zoonotic disease affecting humans and animals and is endemic in many parts of the world including the Gulf Cooperation Council region (GCC). The aim of this study was to identify the species and determine the antimicrobial susceptibility pattern of Brucella strains isolated from clinical specimens, from Qatar.

resultsWe evaluated 231 Brucella isolates. All isolates were identified as B. melitensis. All the isolates were susceptible to doxycycline, tetracycline, streptomycin, gentamicin, trimethoprim / sulfamethoxazole and ciprofloxacin except rifampicin, where 48 % of the strains showed elevated MICs (>1 mg/L). The rifampicin-resistance related hotspots within the rpoB gene were amplified and sequenced using PCR and no rpoB mutations were found in strains with rifampicin MICs of >2 mg/L.

conclusionThis study identified B. melitensis as the etiological agent of brucellosis in Qatar. No resistant isolates were detected among conventionally used antimicrobial agents.

Indexed as

Anti-Bacterial AgentsBacterial ProteinsBrucella melitensisBrucellosisDoxycyclineDrug Resistance, BacterialGentamicinsHumansIn Vitro TechniquesMicrobial Sensitivity TestsQatarRifampinTetracyclineAnti-Bacterial AgentsBacterial ProteinsDoxycyclineGentamicinsRifampinTetracycline

Identifiers

PMID26073177
PMCPMC4466872

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.