Evidence map›Paper›PMID 26072168›Full record

ReviewStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2015

Radiation-induced camptocormia and dropped head syndrome: Review and case report of radiation-induced movement disorders.

Clemens Seidel, Thomas Kuhnt, Rolf-Dieter Kortmann, Kathrin Hering

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Magnetic resonance imaging evaluation of cervical paraspinal muscles in dropped head syndrome.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  2. Review
  3. Conservative treatment for dropped head syndrome.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Article
  4. Dropped head syndrome: a treatment strategy and surgical intervention.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. An Investigation of the Mechanisms of Radiation-Induced Muscle Injury in a Tree Shrew (Dose-response : a publication of International Hormesis Society
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Clemens SeidelDepartment of Radiotherapy and Radiation Oncology, Leipzig University, Stephanstrasse 9a, 04103, Leipzig, Germany. clemens.seidel@medizin.uni-leipzig.de.
Thomas KuhntDepartment of Radiotherapy and Radiation Oncology, Leipzig University, Stephanstrasse 9a, 04103, Leipzig, Germany.
Rolf-Dieter KortmannDepartment of Radiotherapy and Radiation Oncology, Leipzig University, Stephanstrasse 9a, 04103, Leipzig, Germany.
Kathrin HeringDepartment of Radiotherapy and Radiation Oncology, Leipzig University, Stephanstrasse 9a, 04103, Leipzig, Germany.
Leipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn recent years, camptocormia and dropped head syndrome (DHS) have gained attention as particular forms of movement disorders. Camptocormia presents with involuntary forward flexion of the thoracolumbar spine that typically increases during walking or standing and may severely impede walking ability. DHS is characterized by weakness of the neck extensors and a consecutive inability to extend the neck; in severe cases the head is fixed in a "chin to chest position." Many diseases may underlie these conditions, and there have been some reports about radiation-induced camptocormia and DHS.

methodsA PubMed search with the keywords "camptocormia," "dropped head syndrome," "radiation-induced myopathy," "radiation-induced neuropathy," and "radiation-induced movement disorder" was carried out to better characterize radiation-induced movement disorders and the radiation techniques involved. In addition, the case of a patient developing camptocormia 23 years after radiation therapy of a non-Hodgkin's lymphoma of the abdomen is described.

resultsIn total, nine case series of radiation-induced DHS (n = 45 patients) and-including our case-three case reports (n = 3 patients) about radiogenic camptocormia were retrieved. Most cases (40/45 patients) occurred less than 15 years after radiotherapy involving extended fields for Hodgkin's disease.

conclusionThe use of wide radiation fields including many spinal segments with paraspinal muscles may lead to radiation-induced movement disorders. If paraspinal muscles and the thoracolumbar spine are involved, the clinical presentation can be that of camptocormia. DHS may result if there is involvement of the cervical spine. To prevent these disorders, sparing of the spine and paraspinal muscles is desirable.

Indexed as

Abdominal NeoplasmsAdultFollow-Up StudiesHodgkin DiseaseHumansLumbar VertebraeLymphatic IrradiationLymphoma, Non-HodgkinMagnetic Resonance ImagingMaleMiddle AgedMuscle WeaknessMuscular AtrophyMuscular Atrophy, SpinalNeck MusclesParaspinal MusclesCamptocormiaDropped head syndromeRadiation-induced movement disorderRadiation-induced myopathyRadiation-induced neuropathy

Identifiers

PMID26072168
OpenAlexW1569102500

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.