Evidence map›Paper›PMID 26072040›Full record

ReviewPaediatric drugs2015

Psoriasis in Children and Adolescents: Diagnosis, Management and Comorbidities.

I M G J Bronckers, A S Paller, M J van Geel, P C M van de Kerkhof, M M B Seyger

Abstract readReview
In one paragraph

Review in Paediatric drugs, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. The Burden of Pediatric Psoriasis: A Systematic Review.American journal of clinical dermatology · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Anti-TNF agents for paediatric psoriasis.The Cochrane database of systematic reviews · 2015
    Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Shared Pathways between Psoriasis and Atopic Dermatitis.Dermatology practical & conceptual · 2026
    Review
  10. Article
  11. Article
  12. Cell-Free DNA-Based Theranostics for Inflammatory Disorders.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Effects of combined treatment withFood science and biotechnology · 2025
    Article
  19. Review
  20. Pediatric psoriasis: A descriptive, retrospective and multicenter study in ColombiaBiomedica : revista del Instituto Nacional de Salud · 2025
    Article

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

I M G J BronckersDepartment of Dermatology, Radboud University Medical Center, René Descartesdreef 1, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. inge.bronckers@radboudumc.nl.
A S PallerDepartment of Dermatology and Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
M J van GeelDepartment of Dermatology, Radboud University Medical Center, René Descartesdreef 1, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.
P C M van de KerkhofDepartment of Dermatology, Radboud University Medical Center, René Descartesdreef 1, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.
M M B SeygerDepartment of Dermatology, Radboud University Medical Center, René Descartesdreef 1, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
NCATS NIH HHS UL1 TR001422
6 · The paper itself

Abstract

Psoriasis is a common chronic immune-mediated inflammatory skin disorder and begins in childhood in almost one-third of the cases. Although children present with the same clinical subtypes of psoriasis seen in adults, lesions may differ in distribution and morphology, and their clinical symptoms at presentation may vary from those reported by adult patients. Nevertheless, diagnosis of psoriasis is primarily based on clinical features. Pediatric psoriasis can have a profound long-term impact on the psychological health of affected children. Additionally, pediatric psoriasis has been associated with certain comorbidities, such as obesity, hypertension, hyperlipidemia, diabetes mellitus and rheumatoid arthritis, making early diagnosis and management essential. As guidelines are lacking and most (systemic) treatments are not approved for use in children, treatment of pediatric psoriasis remains a challenge. A prospective, multicenter, international registry is needed to evaluate these treatments in a standardized manner and ultimately to develop international guidelines on pediatric psoriasis. This article reviews current concepts in pediatric psoriasis including epidemiology, clinical features, diagnosis, the role of topical and systemic agents and the association with other morbidities in childhood.

Indexed as

ComorbidityPsoriasisAdolescentChildDisease ManagementHumansProspective Studies

Identifiers

PMID26072040
PMCPMC4744260

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.