Evidence map›Paper›PMID 26071426›Full record

ArticleJournal of diabetes science and technology2015

A Low-Cost Inkjet-Printed Glucose Test Strip System for Resource-Poor Settings.

Kayla Gainey Wilson, Patrick Ovington, Delphine Dean

Abstract read
In one paragraph

Article in Journal of diabetes science and technology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kayla Gainey WilsonBioengineering, Clemson University, Clemson, SC, USA Accessible Diagnostics, LLC, Greenville, SC, USA kgainey@g.clemson.edu.
Patrick OvingtonBioengineering, Clemson University, Clemson, SC, USA.
Delphine DeanAccessible Diagnostics, LLC, Greenville, SC, USA Electrical Engineering and Computer Science, Clemson University, Clemson, SC, USA.

Funding

Cardiac-Cell Mechanics at the Single-Cell Level: Properties and InteractionsK25HL092228 · NHLBI · CLEMSON UNIVERSITY · PI DEAN, DELPHINE · 2009 to 2013
$813k
NHLBI NIH HHS K25 HL092228
6 · The paper itself

Abstract

backgroundThe prevalence of diabetes is increasing in low-resource settings; however, accessing glucose monitoring is extremely difficult and expensive in these regions. Work is being done to address the multitude of issues surrounding diabetes care in low-resource settings, but an affordable glucose monitoring solution has yet to be presented. An inkjet-printed test strip solution is being proposed as a solution to this problem.

methodsThe use of a standard inkjet printer is being proposed as a manufacturing method for low-cost glucose monitoring test strips. The printer cartridges are filled with enzyme and dye solutions that are printed onto filter paper. The result is a colorimetric strip that turns a blue/green color in the presence of blood glucose.

resultsUsing a light-based spectroscopic reading, the strips show a linear color change with an R(2) = .99 using glucose standards and an R(2) = .93 with bovine blood. Initial testing with bovine blood indicates that the strip accuracy is comparable to the International Organization for Standardization (ISO) standard 15197 for glucose testing in the 0-350 mg/dL range. However, further testing with human blood will be required to confirm this. A visible color gradient was observed with both the glucose standard and bovine blood experiment, which could be used as a visual indicator in cases where an electronic glucose meter was unavailable.

conclusionsThese results indicate that an inkjet-printed filter paper test strip is a feasible method for monitoring blood glucose levels. The use of inkjet printers would allow for local manufacturing to increase supply in remote regions. This system has the potential to address the dire need for glucose monitoring in low-resource settings.

Indexed as

Health Care CostsAnimalsBiomarkersBlood GlucoseBlood Glucose Self-MonitoringCalibrationCattleColorimetryCost-Benefit AnalysisDeveloping CountriesDiabetes MellitusEquipment DesignFeasibility StudiesHumansLinear ModelsMaterials TestingBiomarkersBlood GlucoseReagent Stripsglucose monitoringinkjet printinglow-cost test strips

Identifiers

PMID26071426
PMCPMC4667310

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.