ArticleThe Plant cell2015
Regulation of Jasmonate-Induced Leaf Senescence by Antagonism between bHLH Subgroup IIIe and IIId Factors in Arabidopsis.
Article in The Plant cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers.
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Who cites it
136 citing papers in PubMed, 317 citations in OpenAlex.
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- Review
- Tomato Leaf Color Diversity as a Functional Trait: Molecular Mechanisms, Physiological Significance, and Environmental Responses.International journal of molecular sciences · 2026Review
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- The BnTFL1-BnJAM3-BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Transcending the jasmonate-mediated growth-defense trade-off: Pathways to unlocking plant potential.Plant communications · 2026Review
- Genome-wide identification and functional characterization of bHLH transcription factors in Herpetospermum pedunculosum under salt stress.BMC plant biology · 2026Article
- Phytochrome B integrates jasmonic acid and warm temperature signaling pathways to regulate cotyledon chloroplast development.Nature communications · 2026Article
- Regulatory Role of Jasmonate Signaling in Dark-, Drought-, and Salt-Induced Leaf Senescence.International journal of molecular sciences · 2026Review
- Molecular mechanisms and application potential of MYC2 transcription factor-mediated plant stress responses.Frontiers in plant science · 2026Review
- Robustness in jasmonate signaling: mechanisms of concerted regulation and implications for crop improvement.aBIOTECH · 2025Review
- Competition Binding of CmbHLH1L and CmNLP6/7L to CmbHLH63 Modulates Leaf Senescence in Chrysanthemum.Plant biotechnology journal · 2025Article
- Transcription factor SmMYC2 regulates secondary cell wall thickening to enhance drought resilience in eggplant.Plant cell reports · 2025Article
- The regulatory role of SlMYC2 in darkness-induced leaf senescence of tomato.Plant cell reports · 2025Article
- Genome-Wide Isoform Switching Reveals SR45-Mediated Splicing Control ofInternational journal of molecular sciences · 2025Article
- SlATG8f coordinates ethylene signaling and chloroplast turnover to drive tomato fruit ripening.Plant cell reports · 2025Article
- Transcriptomic, phenotypic and physiological analyses identify candidate regulators of Dendrobium stigma maturation and pollen-stigma interaction.BMC plant biology · 2025Article
- Unravelling the role of WRKY transcription factors in leaf senescence: Genetic and molecular insights.Journal of advanced research · 2025Review
- Article
76 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plants initiate leaf senescence to relocate nutrients and energy from aging leaves to developing tissues or storage organs for growth, reproduction, and defense. Leaf senescence, the final stage of leaf development, is regulated by various environmental stresses, developmental cues, and endogenous hormone signals. Jasmonate (JA), a lipid-derived phytohormone essential for plant defense and plant development, serves as an important endogenous signal to activate senescence-associated gene expression and induce leaf senescence. This study revealed one of the mechanisms underlying JA-induced leaf senescence: antagonistic interactions of the bHLH subgroup IIIe factors MYC2, MYC3, and MYC4 with the bHLH subgroup IIId factors bHLH03, bHLH13, bHLH14, and bHLH17. We showed that MYC2, MYC3, and MYC4 function redundantly to activate JA-induced leaf senescence. MYC2 binds to and activates the promoter of its target gene SAG29 (SENESCENCE-ASSOCIATED GENE29) to activate JA-induced leaf senescence. Interestingly, plants have evolved an elaborate feedback regulation mechanism to modulate JA-induced leaf senescence: The bHLH subgroup IIId factors (bHLH03, bHLH13, bHLH14, and bHLH17) bind to the promoter of SAG29 and repress its expression to attenuate MYC2/MYC3/MYC4-activated JA-induced leaf senescence. The antagonistic regulation by activators and repressors would mediate JA-induced leaf senescence at proper level suitable for plant survival in fluctuating environmental conditions.
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