Evidence map›Paper›PMID 26071390›Full record

Trial reportSexually transmitted infections2016

The incidence of Trichomonas vaginalis infection in women attending nine sexually transmitted diseases clinics in the USA.

Maria L Alcaide, Daniel J Feaster, Rui Duan, Stephanie Cohen, Chanelle Diaz, Jose G Castro, Matthew R Golden, Sarah Henn, Grant N Colfax, Lisa R Metsch

Registry-linked trialOpen access · greenAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Sexually transmitted infections, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01154296 (Project Aware), which is not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01154296 nacompletednot on this map

Project Aware: HIV Rapid Testing & Counseling in STD Clinics in the U.S. -- an Adaptation of CTN 0032

TypeinterventionalSponsorColumbia UniversityRan2010 to 2012Enrolled5,012ConditionsHIV/AIDS, Sexually Transmitted InfectionsArmsRESPECT-2 Counseling
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Sexually Transmitted Infections Treatment Guidelines, 2021.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2021
    Guideline
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Maria L AlcaideDivision of Infectious Diseases, University of Miami Miller School of Medicine, Miami, Florida, USA.
Daniel J FeasterDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, Florida, USA.
Rui DuanDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, Florida, USA.
Stephanie CohenSan Francisco Department of Public Health, San Francisco, California, USA.
Chanelle DiazUniversity of Miami Miller School of Medicine, Miami, Florida, USA.
Jose G CastroDivision of Infectious Diseases, University of Miami Miller School of Medicine, Miami, Florida, USA.
Matthew R GoldenUniversity of Washington, Seattle, Washington, USA.
Sarah HennWhitman-Walker Health, Washington DC, USA.
Grant N ColfaxSan Francisco Department of Public Health, San Francisco, California, USA.
Lisa R MetschDepartment of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA.
University of Miami · USSan Francisco Department of Public Health · USColumbia University · USUniversity of Washington · USWhitman-Walker Health · US

Funding

The Florida Node Alliance of the National Drug Abuse Treatment Clinical Trials NetworkUG1DA013720 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Daniel J Feaster, Viviana Elizabeth Horigian · 2015 to 2026
$50.6M
The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2003 to 2026
$48.2M
University of Miami Developmental Center for AIDS Research (D-CFAR)P30AI073961 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ALLAN E RODRIGUEZ · 2007 to 2026
$33.8M
HIV Testing and Counseling in STD Clinics: an Adaptation of CTN 0032RC2DA028973 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI FEASTER, DANIEL J · 2009 to 2010
$12.3M
Vaginal practices in HIV positive women in Zambia a bio-behavioral interventionK23HD074489 · NICHD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ALCAIDE, MARIA LUISA · 2012 to 2016
$532k
Identifying Subgroups with Different Responses to HIV Risk Reduction CounselingR21DA038641 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI FEASTER, DANIEL J · 2014 to 2015
$419k
NIAID NIH HHS P30 AI073961NIAID NIH HHS P30AI073961NICHD NIH HHS K23 HD074489NIDA NIH HHS R21 DA038641NIDA NIH HHS RC2 DA028973NIDA NIH HHS UG1 DA013720NIMH NIH HHS P30 MH043520
6 · The paper itself

Abstract

objectivesTrichomoniasis (TV) is associated with an increased risk of acquisition of sexually transmitted diseases (STDs) and HIV. The purpose of this study is to evaluate factors associated with incidence TV among female STD clinic attendees in the USA.

methodsData were collected from women participating in a randomised controlled trial evaluating brief risk reduction counselling at the time of HIV testing to reduce sexually transmitted infections (STIs) incidence in STD clinics. Participants recruited from STD clinics underwent STI testing at baseline and 6-month follow-up. TV testing was performed using Nucleic Acid Amplification Test.

results1704 participants completed study assessments. Prevalence of TV was 14.6%, chlamydia 8.6%, gonorrhoea 3.0%, herpes simplex virus 2 44.7% and HIV 0.4%. Cumulative 6-month incidence of TV was 7.5%. Almost 50% of the incident TV cases had TV at baseline and had received treatment. Factors associated with incidence of TV were having chlamydia, TV and HIV at baseline: TV relative risk (RR)=3.37 (95% CI 2.35 to 4.83, p<0.001); chlamydia RR=1.92 (95% CI 1.23 to 2.99, p=0.04); and HIV=1.59 (95% CI 1.01 to 2.50, p=0.047).

conclusionsPrevalent and incident TV is common among STD clinic attendees; and baseline TV is the main risk factor for incident TV, suggesting high rates of reinfection or treatment failures. This supports the importance of rescreening women after treatment for TV, evaluating current treatment regimens and programmes to ensure treatment of sexual partners. CLINICAL TRIAL NUMBER: NCT01154296.

Indexed as

Directive CounselingSexual PartnersAdultFemaleHumansPrevalenceRisk FactorsRisk Reduction BehaviorTrichomonas vaginalisTrichomonas VaginitisUnited StatesEPIDEMIOLOGY (CLINICAL)TRICHOMONASWOMEN

Identifiers

PMID26071390
PMCPMC4874593
OpenAlexW2258110347

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.