Evidence map›Paper›PMID 26071114›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2016

Do myocardial PET-MR and PET-CT FDG images provide comparable information?

Jorge D Oldan, Shetal N Shah, Richard C Brunken, Frank P DiFilippo, Nancy A Obuchowski, Michael A Bolen

Abstract readComparative StudyEvaluation Study
PubMed Publisher
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Assessing the qualitative and quantitative impacts of simple two-class vs multiple tissue-class MR-based attenuation correction for cardiac PET/MR.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  2. Assessing time-of-flight signal-to-noise ratio gains within the myocardium and subsequent reductions in administered activity in cardiac PET studies.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  3. Does time-of-flight improve image quality in the heart?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  4. The effect of time-of-flight and point spread function modeling onJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  5. Review
  6. Differences in polar-map patterns using the novel technologies for myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  7. MR/PET Imaging of the Cardiovascular System.JACC. Cardiovascular imaging · 2017
    Review
  8. PET/MR: Yet another Tesla?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Review
  9. The foundation layer of quantitative cardiac PET/MRI: Attenuation correction. Again.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  10. Review
  11. Time to move to PET-MR for cardiovascular imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016
    Article
  12. Analysis of the 17-segment left ventricle model using generalized estimating equations.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016
    Article
  13. Recent Advances in Nuclear Cardiology.Nuclear medicine and molecular imaging · 2016
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jorge D OldanDepartment of Cardiovascular Imaging, Cleveland Clinic Foundation, 9500 Euclid Ave.-J14, Cleveland, OH, 44195, USA. Joldan9@gmail.com.
Shetal N ShahDepartments of Radiology and Nuclear Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.
Richard C BrunkenDepartment of Nuclear Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.
Frank P DiFilippoDepartment of Nuclear Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.
Nancy A ObuchowskiDepartment of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, USA.
Michael A BolenDepartment of Cardiovascular Imaging, Cleveland Clinic Foundation, 9500 Euclid Ave.-J14, Cleveland, OH, 44195, USA.
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlthough positron emission tomography PET-MR imaging is emerging into clinical practice, many aspects of this imaging technique such as attenuation correction have yet to be validated for myocardial imaging. Thus, it is uncertain whether PET-MR FDG images provide clinical information which is comparable to PET-CT FDG images. The study goal was to systematically compare relative myocardial FDG concentrations obtained from cardiac PET-MR images to those derived from same day PET-CT images.

methodsMyocardial FDG images of 27 patients undergoing PET-CT imaging, followed by PET-MR imaging 42 ± 13 minutes later as part of a prospective oncology study were analyzed. Mean segmental standardized uptake measurements (SUVmean) were obtained in each of the 17 standard myocardial segments and normalized to the brightest segment.

resultsNormalized segmental SUVmean values did not differ significantly between the PET-MR and PET-CT images (mean difference 0.002, P = .826). The specific segment was a marginally significant predictor of the differences (P = .057), with the largest difference in the anteroseptal basal segment.

conclusionsPET-MR, vis-à-vis PET-CT, does not significantly raise segmental uptake relative to the brightest segment, suggesting that PET-MR can be used similarly to PET-CT for applications where relative uptake is important.

Indexed as

AdolescentAdultAgedCardiac Imaging TechniquesComputer SimulationFemaleFluorodeoxyglucose F18HeartHumansImage EnhancementImage Interpretation, Computer-AssistedMaleMiddle AgedModels, CardiovascularMyocardiumPositron Emission Tomography Computed TomographyFluorodeoxyglucose F18RadiopharmaceuticalsAttenuation and scatter correctionimage qualityinstrumentation: PETPET/CT imagingradionuclides

Identifiers

PMID26071114
OpenAlexW571653355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.