Evidence map›Paper›PMID 26070460›Full record

ArticleJournal of medical case reports2015

Chemotherapeutic treatment of colorectal cancer in pregnancy: case report.

Ziyad Makoshi, Claire Perrott, Khadija Al-Khatani, Fadia Al-Mohaisen

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 36 citations in OpenAlex.

  1. Colorectal Cancer Treatment During Pregnancy.Journal of the advanced practitioner in oncology · 2026
    Article
  2. Review
  3. Article
  4. Colon Cancer and Pregnancy.Clinics in colon and rectal surgery · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Ziyad MakoshiDepartment of Surgery, College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia. zmakoshi@gmail.com.
Claire PerrottSouthampton School of Medicine, University of Southampton, Southampton, UK. c.perrott@live.co.uk.
Khadija Al-KhataniDepartment of Obstetrics and Gynecology, Women's Specialist Hospital, King Fahad Medical City, Riyadh, Saudi Arabia. khadija.alkhatani@gmail.com.
Fadia Al-MohaisenDepartment of Pathology, King Khalid University Hospital, Riyadh, Saudi Arabia. fadia.almohaisen@gmail.com.
King Fahad Specialist Hospital · SAKing Khalid University Hospital · SAOttawa Hospital · CAUniversity of Southampton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionColon cancer in pregnancy is uncommon. Only a small number of case reports have been published in the literature on the use of chemotherapeutic drugs during pregnancy. Reports of such cases assist clinicians in further investigating the use of chemotherapy in pregnancy. CASE PRESENTATION: FOLFOX-6 was administered to a pregnant, 33-year-old Saudi woman with metastatic colon cancer from 22 to 30 weeks of gestation. Her cancer was diagnosed during her pregnancy. She tolerated the chemotherapy well and delivered a full-term baby girl with no obvious harm, and normal development was documented at her 2-year follow-up examination.

conclusionColon cancer during pregnancy is not easily detected and is difficult to manage. A detailed history and high clinical suspicion are needed in patients who present with symptoms and signs suggestive of malignancy. A multidisciplinary approach with patient involvement is needed to decrease morbidity and mortality caused by both treatment and the cancer in the mother and to limit side effects for the fetus. Further data and long-term follow-up are needed to better understand the potential long-term side effects of chemotherapeutic drugs on offspring.

Indexed as

PregnancyAdenocarcinomaAdultAntineoplastic Combined Chemotherapy ProtocolsColorectal NeoplasmsFemaleFluorouracilHumansLeucovorinLiver NeoplasmsOrganoplatinum CompoundsOvarian NeoplasmsOvariectomyOxaliplatinPregnancy Complications, NeoplasticFluorouracilLeucovorinOrganoplatinum CompoundsOxaliplatin

Identifiers

PMID26070460
PMCPMC4469397
OpenAlexW1520636663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.