Evidence map›Paper›PMID 26070453›Full record

ReviewCurrent hypertension reports2015

The Role of Central Nervous System Mechanisms in Resistant Hypertension.

Dagmara Hering, Markus Schlaich

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Current hypertension reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Renal denervation based on experimental rationale.Hypertension research : official journal of the Japanese Society of Hypertension · 2021
    Review
  6. Review
  7. Neurogenic hypertension: pathophysiology, diagnosis and management.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2018
    Review
  8. Review
  9. Increased (pro)renin receptor expression in the subfornical organ of hypertensive humans.American journal of physiology. Heart and circulatory physiology · 2018
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Renal denervation for resistant hypertension: yes.Internal and emergency medicine · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Dagmara HeringSchool of Medicine and Pharmacology - Royal Perth Hospital Unit, The University of Western Australia, Level 3 MRF Building, Rear 50 Murray Street, Perth, WA, 6000 MDBP: M570, Australia, dagmara.hering@uwa.edu.au.
Markus Schlaich
University of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arterial hypertension remains a primary global health problem with significant impact on cardiovascular morbidity and mortality. The low rate of hypertension control and failure to achieve target blood pressure levels particularly among high-risk patients with resistant hypertension has triggered renewed interest in unravelling the underlying mechanisms to implement therapeutic approaches for better patient management. Here, we summarize the crucial role of neurogenic mechanisms in drug-resistant hypertension, with a specific focus on central control of blood pressure, the factors involved in central integration of afferent signalling to increase sympathetic drive in resistant hypertension, and briefly review recently introduced interventional strategies distinctively targeting sympathetic activation.

Indexed as

Blood PressureCentral Nervous SystemDeep Brain StimulationHumansHypertensionKidneyOxidative Stress

Identifiers

PMID26070453
OpenAlexW606921359

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.