Evidence map›Paper›PMID 26070444›Full record

ArticleMolecular aspects of medicine

Non-pharmacological interventions for adults with mild cognitive impairment and early stage dementia: An updated scoping review.

Juleen Rodakowski, Ester Saghafi, Meryl A Butters, Elizabeth R Skidmore

2 registry-linked trialsAbstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular aspects of medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 78 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04185298 naterminatednot on this map

Mobile Technology-Based Simultaneous Aerobic Exercise and Memory Training Intervention for Older Adults With Mild Cognitive Impairment

TypeinterventionalSponsorJennifer BramenRan2019 to 2023Enrolled12ConditionsAmnestic Mild Cognitive ImpairmentArmsmSIM intervention plus activity monitoring, Activity monitoring
NCT05992402 narecruitingnot on this map

Readiness Brain Operation Optimization Training (ReBOOT) for Epilepsy Surgery

TypeinterventionalSponsorKayela ArrottaRan2023 to 2028Enrolled64ConditionsEpilepsyArmsReBOOT program
3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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  18. Modified cognitive behavioral therapy (M-CBT) for cocaine dependence: Development of treatment for cognitively impaired users and results from a Stage 1 trial.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2018
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18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Juleen RodakowskiDepartment of Occupational Therapy, School of Health & Rehabilitation Sciences, University of Pittsburgh (Rodakowski, Skidmore), Pittsburgh, PA, USA; Clinical and Translational Science Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Ester SaghafiHealth Sciences Library System, University of Pittsburgh (Saghafi), Pittsburgh, PA, USA.
Meryl A ButtersDepartment of Psychiatry, School of Medicine, University of Pittsburgh (Butters), Pittsburgh, PA, USA.
Elizabeth R SkidmoreDepartment of Occupational Therapy, School of Health & Rehabilitation Sciences, University of Pittsburgh (Rodakowski, Skidmore), Pittsburgh, PA, USA; Clinical and Translational Science Institute, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: skidmore@pitt.edu.

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Caterina Rosano · 2004 to 2026
$28.6M
University of Pittsburgh Clinical and Translational Science InstitutionKL2TR000146 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$8.7M
RESEARCH METHODS COREP30MH090333 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REYNOLDS, CHARLES F. · 2011 to 2015
$8.3M
NCATS NIH HHS KL2 TR000146NCATS NIH HHS KL2TR000146NCATS NIH HHS UL1 TR000005NIA NIH HHS P30 AG024827NIMH NIH HHS P30 MH090333
6 · The paper itself

Abstract

The purpose of this scoping review was to examine the science related to non-pharmacological interventions designed to slow decline for older adults with Mild Cognitive Impairment or early-stage dementia. We reviewed 32 unique randomized controlled trials that employed cognitive training (remediation or compensation approaches), physical exercise, or psychotherapeutic interventions that were published before November 2014. Evidence suggests that cognitive training focused on remediation and physical exercise interventions may promote small improvements in selected cognitive abilities. Cognitive training focused on compensation interventions and selected psychotherapeutic interventions may influence how cognitive changes impact daily living. However, confidence in these findings is limited due to methodological limitations. To better assess the value of non-pharmacological interventions for this population, we recommend: (1) adoption of universal criteria for "early stage cognitive decline" among studies, (2) adherence to guidelines for the conceptualization, operationalization, and implementation of complex interventions, (3) consistent characterization of the impact of interventions on daily life, and (4) long-term follow-up of clinical outcomes to assess maintenance and meaningfulness of reported effects over time.

Indexed as

ExercisePsychotherapeutic ProcessesAgedAged, 80 and overAlzheimer DiseaseCognitive DysfunctionDementiaHumansRandomized Controlled Trials as TopicAlzheimer's diseaseBehavioral interventionsCognitive rehabilitationDementiaMild cognitive impairmentNon-pharmacological interventions

Identifiers

PMID26070444
PMCPMC4600436

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.