Evidence map›Paper›PMID 26070289›Full record

ArticleJournal of neurology2015

Quality of life in patients with progressive supranuclear palsy: one-year follow-up.

Tatjana Pekmezović, Milica Ječmenica-Lukić, Igor Petrović, Vladana Špica, Aleksandra Tomić, Vladimir S Kostić

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Psychometric properties and clinical correlates of the Frontal Behaviour Inventory in progressive supranuclear palsy: data from the PSP-NET.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  3. Article
  4. Article
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  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Managing cognition in progressive supranuclear palsy.Neurodegenerative disease management · 2016
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tatjana PekmezovićInstitute of Epidemiology, Faculty of Medicine, University of Belgrade, Višegradska 26A, Belgrade, 11000, Serbia.
Milica Ječmenica-LukićInstitute of Neurology, Clinical Centre of Serbia, Faculty of Medicine, School of Medicine, University of Belgrade, Ul. Dr Subotića 6, 11000, Belgrade, Serbia.
Igor PetrovićInstitute of Neurology, Clinical Centre of Serbia, Faculty of Medicine, School of Medicine, University of Belgrade, Ul. Dr Subotića 6, 11000, Belgrade, Serbia.
Vladana ŠpicaInstitute of Neurology, Clinical Centre of Serbia, Faculty of Medicine, School of Medicine, University of Belgrade, Ul. Dr Subotića 6, 11000, Belgrade, Serbia.
Aleksandra TomićInstitute of Neurology, Clinical Centre of Serbia, Faculty of Medicine, School of Medicine, University of Belgrade, Ul. Dr Subotića 6, 11000, Belgrade, Serbia.
Vladimir S KostićInstitute of Neurology, Clinical Centre of Serbia, Faculty of Medicine, School of Medicine, University of Belgrade, Ul. Dr Subotića 6, 11000, Belgrade, Serbia. vladimir.s.kostic@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this prospective cohort study that included 46 patients with progressive supranuclear palsy (PSP) was to estimate which demographic and clinical factors were the main contributors to the health-related quality of life (HRQoL) and how did the HRQoL change over a follow-up period of 1 year in these patients. The hierarchical regression analyses showed that the final models demonstrated that gender, included clinical variables and psychiatric/neuropsychological scales, accounted for 68% of the variance in the Physical Composite Score and 73% of the variance of the Mental Composite Score of the 36-item Short Form Health Survey (SF-36). Among variables in both final models, only the score of the Apathy Evaluation Scale showed statistically significant negative predictive value (p < 0.05). Changes in the HRQoL scores were assessed in 28 PSP patients who completed 1-year follow-up period after the baseline examination. Statistically significant decline in the HRQoL was detected for the following scales of the SF-36: physical functioning, vitality, social functioning, and role emotional, as well as in both composite scores (Physical Composite Score and Mental Composite Score). The analyses of magnitude of changes in the HRQoL during 1-year follow-up period showed large effect size (≥0.80) for total scores, as well as for the physical functioning, vitality, and social functioning. In conclusion, despite certain limitations, our study provided some new insights into potential predictors of the HRQoL and its longitudinal changes in patients with PSP.

Indexed as

Models, TheoreticalAgedAged, 80 and overApathyDisability EvaluationFemaleFollow-Up StudiesHealth StatusHumansMaleMiddle AgedProspective StudiesQuality of LifeSupranuclear Palsy, ProgressiveSurveys and QuestionnairesFollow-upPredictorsProgressive supranuclear palsyQuality of life

Identifiers

PMID26070289

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.