Evidence map›Paper›PMID 26069718›Full record

ReviewWorld journal of diabetes2015

Management of critically ill patients with type 2 diabetes: The need for personalised therapy.

Palash Kar, Karen L Jones, Michael Horowitz, Adam M Deane

Open access · diamondAbstract readReview
In one paragraph

Review in World journal of diabetes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Pre-Existing Diabetes Alters Pulmonary Inflammatory Gene Expression Priming for Injury.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Study protocol and statistical analysis plan for the Liberal Glucose Control in Critically Ill Patients with Pre-existing Type 2 Diabetes (LUCID) trial.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2020
    Article
  8. Observational
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Palash KarPalash Kar, Adam M Deane, Discipline of Acute Care Medicine, Level 5, Eleanor Harrald Building, University of Adelaide, South Australia 5000, Australia.
Karen L JonesPalash Kar, Adam M Deane, Discipline of Acute Care Medicine, Level 5, Eleanor Harrald Building, University of Adelaide, South Australia 5000, Australia.
Michael HorowitzPalash Kar, Adam M Deane, Discipline of Acute Care Medicine, Level 5, Eleanor Harrald Building, University of Adelaide, South Australia 5000, Australia.
Adam M DeanePalash Kar, Adam M Deane, Discipline of Acute Care Medicine, Level 5, Eleanor Harrald Building, University of Adelaide, South Australia 5000, Australia.
The University of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Critical illness in patients with pre-existing diabetes frequently causes deterioration in glycaemic control. Despite the prevalence of diabetes in patients admitted to hospital and intensive care units, the ideal management of hyperglycaemia in these groups is uncertain. There are data that suggest that acute hyperglycaemia in critically ill patients without diabetes is associated with increased mortality and morbidity. Exogenous insulin to keep blood glucose concentrations < 10 mmol/L is accepted as standard of care in this group. However, preliminary data have recently been reported that suggest that chronic hyperglycaemia may result in conditioning, which protects these patients against damage mediated by acute hyperglycaemia. Furthermore, acute glucose-lowering to < 10 mmol/L in patients with diabetes with inadequate glycaemic control prior to their critical illness appears to have the capacity to cause harm. This review focuses on glycaemic control in critically ill patients with type 2 diabetes, the potential for harm from glucose-lowering and the rationale for personalised therapy.

Indexed as

Critically illDiabetesIntensive careManagementPersonalised therapy

Identifiers

PMID26069718
PMCPMC4458498
OpenAlexW572990402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.