ArticleJournal of ophthalmic inflammation and infection2015
Bilateral papillitis and unilateral focal chorioretinitis as the presenting features of syphilis.
Article in Journal of ophthalmic inflammation and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Article
- Syphilitic retinitis presentations: punctate inner retinitis and posterior placoid chorioretinitis.International ophthalmology · 2021Article
- Eyes As the Window to Syphilis: A Rare Case of Ocular Syphilis As the Initial Presentation of Syphilis.Cureus · 2020Article
- Incipient Syphilitic Papillitis.Neuro-ophthalmology (Aeolus Press) · 2020Article
- Spectral optical coherence tomography findings in an adult patient with syphilitic bilateral posterior uveitis and unilateral punctate inner retinitis.American journal of ophthalmology case reports · 2019Article
- Coexistence of Papillitis and Posterior Placoid Chorioretinopathy as the Presenting Symptoms of Syphilis-Human Immunodeficiency Virus Coinfection.Neuro-ophthalmology (Aeolus Press) · 2019Article
- A Rare Case of Neurosyphilis with Ocular Involvement in a Patient with HIV Infection and New Onset Syphilis.Cureus · 2019Article
- Spectral optical coherence tomography findings in an elderly patient with syphilitic bilateral chronic panuveitis.American journal of ophthalmology case reports · 2018Article
- Syphilis-Related Eye Disease Presenting as Bilateral Papilledema, Retinal Nerve Fiber Layer Hemorrhage, and Anterior Uveitis in a Penicillin-Allergic Patient.Case reports in infectious diseases · 2018Article
- Bilateral Chorioretinitis as Syphilis Presentation: Multimodal Characterization and Therapy Response.Journal of clinical and diagnostic research : JCDR · 2016Article
- Clinical Manifestations and Treatment Outcomes of Syphilitic Uveitis in a Chinese Population.Journal of ophthalmology · 2016Article
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSyphilis is a multisystem bacterial infection caused by Treponema pallidum. The incidence of infection in the United States has risen by more than 75% since the year 2000, when it was at a low of 2.1 per 100,000 people. Ocular involvement may occur in any stage of infection and may present in a variety of ways, with posterior uveitis being the most common manifestation. We report a case of ocular syphilis infection with an unusual presentation of bilateral non-granulomatous panuveitis with papillitis and unilateral focal chorioretinitis.
findingsThis is a retrospective case report with literature review. A 39-year-old Caucasian female presented with a 2-week history of bilateral ocular flashes and left eye pain. Dilated fundus examination revealed mild optic disc edema in both eyes, the right eye more than the left. In the left eye, there was an area of retinal elevation and whitening involving the peripheral retina. Fluorescein angiography, B-scan ultrasonography, and ocular coherence tomography were performed, and laboratory tests were ordered based on the clinical presentation. After rapid plasma reagin (RPR) and fluorescent treponemal antibody absorption (FTA-Abs) were positive, syphilitic uveitis was confirmed, and the patient was admitted for a 14-day course of high-dose intravenous penicillin G.
conclusionsThe first signs and symptoms of syphilis may be ocular, which can lead to a diagnostic challenge. A high index of suspicion is the key for early diagnosis of ocular syphilis. Prompt treatment with intravenous penicillin G is highly effective in resolving the infection.
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