Evidence map›Paper›PMID 26069500›Full record

ArticleCancer nanotechnology

Antileukemic potential of PEGylated gold nanoparticle conjugated with protein toxin (NKCT1) isolated from Indian cobra (

Tanmoy Bhowmik, Partha Pratim Saha, Anjan Dasgupta, Antony Gomes

Abstract read
In one paragraph

Article in Cancer nanotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Anticancer potential of nanogold conjugated toxin GNP-NN-32 fromThe journal of venomous animals and toxins including tropical diseases · 2020
    Article
  6. Article
  7. Article
  8. Article
  9. Toxicology reports · 2014
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tanmoy BhowmikLaboratory of Toxinology & Experimental Pharmacodynamics, Department of Physiology, University of Calcutta, 92 APC Road, Kolkata, 700009 India.
Partha Pratim SahaLaboratory of Toxinology & Experimental Pharmacodynamics, Department of Physiology, University of Calcutta, 92 APC Road, Kolkata, 700009 India.
Anjan DasguptaDepartment of Biochemistry, University of Calcutta, 35 Ballygunge Circular Road, Ballygunge, Kolkata, 700019 India.
Antony GomesLaboratory of Toxinology & Experimental Pharmacodynamics, Department of Physiology, University of Calcutta, 92 APC Road, Kolkata, 700009 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Limited efficacy of current first-line treatment for leukemia calls attention for further development of efficient strategies. Recently, much attention has been given to nanoparticle-based drug delivery systems loaded with dual drugs to improve current disease therapies by overcoming toxicity. In the present study, we document to explore an approach to conjugate gold nanoparticles (GNPs) with protein toxin (NKCT1), a protein toxin from the Indian cobra (

Indexed as

ApoptosisCell cycleFlow cytometryGNP-NKCT1Leukemic cellNanoparticle

Identifiers

PMID26069500
PMCPMC4451861

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.