ArticleCancer nanotechnology
Anti-cancer studies of noble metal nanoparticles synthesized using different plant extracts.
Article in Cancer nanotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Biofabrication ofLife (Basel, Switzerland) · 2025Article
- Modification of Gold Nanoparticles Provides Antioxidant and Anti-Tumor Properties.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Green Synthesis of Gold Nanoparticles UsingPharmaceuticals (Basel, Switzerland) · 2025Article
- Fucoidan-Based Gold Nanoparticles: Antioxidant and Anticancer Potential fromPharmaceutics · 2025Article
- Bipartite Graph Analysis of the Virus-Host Protein Interaction Network to Identify Key Proteins Mediating the Infection.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Global Research Trends and Recent Advances in Medicinal Plant-Synthesized Nanoparticles for Cancer Treatment.Plants (Basel, Switzerland) · 2024Article
- An Overview of Metallic Nanoparticles: Classification, Synthesis, Applications, and their Patents.Recent patents on nanotechnology · 2024Review
- The Effects of Clove and Its Constituents on Reproductive System: a Comprehensive Review.Reproductive sciences (Thousand Oaks, Calif.) · 2023Review
- Anticancer potential of biologically synthesized silver nanoparticles using Lantana camara leaf extract.Progress in biomaterials · 2023Article
- Green Synthesis of Magnesium Oxide Nanoparticles by UsingBioengineering (Basel, Switzerland) · 2023Article
- Emerging Trends in Advanced Translational Applications of Silver Nanoparticles: A Progressing Dawn of Nanotechnology.Journal of functional biomaterials · 2023Review
- Revisiting the Green Synthesis of Nanoparticles: Uncovering Influences of Plant Extracts as Reducing Agents for Enhanced Synthesis Efficiency and Its Biomedical Applications.International journal of nanomedicine · 2023Review
- Plant-Based Synthesis of Gold Nanoparticles and Theranostic Applications: A Review.Molecules (Basel, Switzerland) · 2022Review
- Green synthesis of silver nanoparticles using Rhodiola imbricata and Withania somnifera root extract and their potential catalytic, antioxidant, cytotoxic and growth-promoting activities.Bioprocess and biosystems engineering · 2022Article
- Engineering the Single Domain Antibodies Targeting Receptor Binding Motifs Within the Domain III of West Nile Virus Envelope Glycoprotein.Frontiers in microbiology · 2022Article
- The nanocomposites designs of phytomolecules from medicinal and aromatic plants: promising anticancer-antiviral applications.Beni-Suef University journal of basic and applied sciences · 2022Review
- A Review on Green Synthesis, Characterization and Anticancer Application of Metallic Nanoparticles.Applied biochemistry and biotechnology · 2021Review
- Silver Nanoparticles fromNanomaterials (Basel, Switzerland) · 2021Article
- Green Biosynthesis of Silver Nanoparticles Using Leaf Extract ofBiomolecules · 2021Article
- Green Synthesis of Silver Nanoparticles UsingNanomaterials (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
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Abstract
Biofunctionalized gold and silver nanoparticles synthesized using different plant extracts of guava and clove in vitro anti-cancer efficacy against four different cancer cell lines human colorectal adenocarcinoma, human kidney, human chronic myelogenous, leukemia, bone marrow, and human cervix have been studied and reported. The present experimental study suggests that flavonoids functionalized gold nanoparticles synthesized using aqueous clove buds extract are more potential than guava leaf extract towards anti-cancer activities. The microscopic and 2,3-bis (2-methoxy-4-nitro-5-sulfophenyl)-5-[(phenylamino)carbonyl]-2H-tetrazolium hydroxide (XTT) assay infer that the functionalized irregular shaped gold nanoparticles synthesized with aqueous clove bud extract showed a satisfactory anti-cancer effect on all the cell lines. The silver nanoparticles synthesized using same extracts are devoid of anti-cancer activity. The XTT assay revealed dose-dependent cytotoxicity to cancer cell lines. The study revealed that the free radicals generated by gold nanoparticles are responsible for anti-cancer effect. To confirm the free-radical scavenging efficacy of gold nanoparticle, nitric oxide assay is followed. We observed that the gold nanoparticles swabbed the free radicals in dose-dependent manner. With continued improvements, these nanoparticles may prove to be potential anti-cancer agents.
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