ArticleJournal of neurology, neurosurgery, and psychiatry2016
Old benefit as much as young patients with stroke from high-intensity neurorehabilitation: cohort analysis.
Article in Journal of neurology, neurosurgery, and psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03641651 (Feasibility and Cost Description of Intensive Rehabilitation Involving New Technologies in Patients With Sub-acute Stroke), which is not on this map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Feasibility and Cost Description of Intensive Rehabilitation Involving New Technologies in Patients With Sub-acute Stroke:A Multicenter Single Arm Trial of the Swiss RehabTech Initiative
Who cites it
19 citing papers in PubMed.
- A decision-neuroscientific intervention to improve cognitive recovery after stroke.Brain : a journal of neurology · 2021Trial
- Inducing illusory control ensures persistence when rewards fade and when others outperform us.Psychonomic bulletin & review · 2020Trial
- Effectiveness of rehabilitation dose heterogeneity for improving functional outcomes of patients with acute stroke: a nationwide observational study.Scientific reports · 2025Observational
- Age Is Not the Limit-Functional Outcomes and Discharge Predictors in a Neurorehabilitation Cohort of Mixed Ages.Archives of rehabilitation research and clinical translation · 2025Article
- Mapping the Role of Robot-Assisted Gait Training in Post-Stroke Recovery Among Elderly Patients: A Scoping Review.Journal of clinical medicine · 2025Review
- International stakeholder consultation on models of rehabilitation service delivery to foster healthy ageing: results of a cross-sectional survey involving 124 countries and all World Health Organization regions.European journal of physical and rehabilitation medicine · 2025Observational
- Hashimoto's Encephalopathy: Clinical Features, Therapeutic Strategies, and Rehabilitation Approaches.Biomedicines · 2025Review
- [Slow demographic change and neurological rehabilitation-Part 1: state of affairs].Der Nervenarzt · 2023Review
- COVID-19 Reveals Opportunities for Better Care of Stroke Patients–Direct Transfer to Postacute Rehabilitation, Reduction in Length of Stay, and Treatment Outcomes.Deutsches Arzteblatt international · 2021Article
- [Second look: practical diagnostic and therapeutic checks in neurorehabilitation].Der Nervenarzt · 2020Review
- Contributing factors to quality of life after vertebral artery dissection: a prospective comparative study.BMC neurology · 2019Article
- Effect of rehabilitation therapy and nursing intervention on postoperative recovery of patients with hypertensive intracerebral hemorrhage.Experimental and therapeutic medicine · 2019Article
- [Integrated neurorehabilitation improves efficacy of treatment].Der Nervenarzt · 2019Article
- Conquering the inner couch potato: precommitment is an effective strategy to enhance motivation for effortful actions.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
- Research in the Acute Rehabilitation Setting: a Bridge Too Far?Current neurology and neuroscience reports · 2019Review
- Rehabilitation and the Neural Network After Stroke.Translational stroke research · 2017Review
- Integrated Health Care Management of Moderate to Severe TBI in Older Patients-A Narrative Review.Current neurology and neuroscience reports · 2017Review
- Brain regions important for recovery after severe post-stroke upper limb paresis.Journal of neurology, neurosurgery, and psychiatry · 2017Article
- The contribution of lesion location to upper limb deficit after stroke.Journal of neurology, neurosurgery, and psychiatry · 2016Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveIn current clinical practice, old patients with stroke are less frequently admitted to neurorehabilitation units following acute care than younger patients based on an assumption that old age negatively impacts the benefit obtained from high-intensity neurorehabilitation. Our objective was to test this assumption empirically in a large sample of patients with stroke.
methodsFunctional recovery during 4 weeks of inpatient neurorehabilitation was assessed with the Barthel Index (BI) in 422 middle-aged (<65 years), 1399 old (65-80 years) and 473 very old (>80 years) patients with stroke. Overall functional recovery, recovery patterns and the relationship between therapy intensity and recovery were statistically compared between the three age groups.
resultsOverall functional recovery was statistically equivalent in middle-aged, old and very old patients (average improvement in BI total score: middle-aged: 15 points; old: 15 points; very old: 14 points). A novel item-wise logistic regression analysis (see Pedersen, Severinsen & Nielsen, 2014, Neurorehabil Neural Repair) revealed that this was true for 9 of the 10 everyday functions assessed by the BI. Furthermore, functional recovery was predicted by the amount of therapy (R=0.14; p=0.0001), and age did not moderate this relationship between therapy intensity and recovery (p=0.70).
conclusionsOld and even very old patients with stroke benefit from specialised inpatient neurorehabilitation and high amounts of therapy in the same degree as younger patients. Contrary to current clinical practice, old age should not be a criterion against admission to a neurorehabilitation unit following acute stroke treatment.
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