Evidence map›Paper›PMID 26068455›Full record

ArticleInternational journal of molecular sciences2015

Comparison of Selective Laser Melted Titanium and Magnesium Implants Coated with PCL.

Julia Matena, Svea Petersen, Matthias Gieseke, Michael Teske, Martin Beyerbach, Andreas Kampmann, Hugo Murua Escobar, Nils-Claudius Gellrich, Heinz Haferkamp, Ingo Nolte

Abstract readComparative Study
In one paragraph

Article in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Julia MatenaSmall Animal Clinic, University of Veterinary Medicine Hannover, Foundation, D-30559 Hannover, Germany. julia.matena@tiho-hannover.de.
Svea PetersenFaculty of Engineering and Computer Science, Osnabrueck University of Applied Sciences, D-49076 Osnabrueck, Germany. s.petersen@hs-osnabrueck.de.
Matthias GiesekeInstitute for Biomedical Engineering, Rostock University Medical Center, D-18119 Rostock, Germany. m.gieseke@lzh.de.
Michael TeskeMaterials and Processes Department, Laser Zentrum Hannover e.V., D-30419 Hannover, Germany. michael.teske@uni-rostock.de.
Martin BeyerbachInstitute for Biometry, Epidemiology and Information Processing, University of Veterinary Medicine Hannover, Foundation, D-30559 Hannover, Germany. martin.beyerbach@tiho-hannover.de.
Andreas KampmannClinic for Cranio-Maxillo-Facial Surgery, Hannover Medical School, D-30625 Hannover, Germany. kampmann.andreas@mh-hannover.de.
Hugo Murua EscobarSmall Animal Clinic, University of Veterinary Medicine Hannover, Foundation, D-30559 Hannover, Germany. hugo.murua.escobar@med.uni-rostock.
Nils-Claudius GellrichClinic for Cranio-Maxillo-Facial Surgery, Hannover Medical School, D-30625 Hannover, Germany. gellrich.nils-claudius@mh-hannover.de.
Heinz HaferkampInstitut fuer Werkstoffkunde, Leibniz Universitaet Hannover, D-30823 Hannover, Germany. haferkamp@iw.uni-hannover.de.
Ingo NolteSmall Animal Clinic, University of Veterinary Medicine Hannover, Foundation, D-30559 Hannover, Germany. ingo.nolte@tiho-hannover.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Degradable implant material for bone remodeling that corresponds to the physiological stability of bone has still not been developed. Promising degradable materials with good mechanical properties are magnesium and magnesium alloys. However, excessive gas production due to corrosion can lower the biocompatibility. In the present study we used the polymer coating polycaprolactone (PCL), intended to lower the corrosion rate of magnesium. Additionally, improvement of implant geometry can increase bone remodeling. Porous structures are known to support vessel ingrowth and thus increase osseointegration. With the selective laser melting (SLM) process, defined open porous structures can be created. Recently, highly reactive magnesium has also been processed by SLM. We performed studies with a flat magnesium layer and with porous magnesium implants coated with polymers. The SLM produced magnesium was compared with the titanium alloy TiAl6V4, as titanium is already established for the SLM-process. For testing the biocompatibility, we used primary murine osteoblasts. Results showed a reduced corrosion rate and good biocompatibility of the SLM produced magnesium with PCL coating.

Indexed as

Bone-Implant InterfaceAnimalsCells, CulturedCoated Materials, BiocompatibleLasersMagnesiumMiceOsseointegrationPolyestersTitaniumCoated Materials, BiocompatibleMagnesiumpolycaprolactonePolyestersTitaniumlive cell imagingmagnesium implantosteoblastpoly-3-hydroxybutyratepolycaprolactonetitanium implant

Identifiers

PMID26068455
PMCPMC4490495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.