Evidence map›Paper›PMID 26068204›Full record

ArticleIEEE transactions on medical imaging2015

Retinal Artery-Vein Classification via Topology Estimation.

Rolando Estrada, Michael J Allingham, Priyatham S Mettu, Scott W Cousins, Carlo Tomasi, Sina Farsiu

Abstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
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  5. Universal Vessel Segmentation for Multi-Modality Retinal Images.IEEE transactions on image processing : a publication of the IEEE Signal Processing Society · 2025
    Article
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  15. Article
  16. Differential artery-vein analysis in quantitative retinal imaging: a review.Quantitative imaging in medicine and surgery · 2021
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rolando Estrada
Michael J Allingham
Priyatham S Mettu
Scott W Cousins
Carlo Tomasi
Sina Farsiu

Funding

NEI Mentored Clincial Scientist Development Program Award (K12)K12EY016333 · NEI · DUKE UNIVERSITY · PI COUSINS, SCOTT W · 2004 to 2013
$5.4M
Computer Aided Classification of Diabetic Macular EdemaR01EY022691 · NEI · DUKE UNIVERSITY · PI FARSIU, SINA · 2012 to 2016
$1.9M
NEI NIH HHS K12 EY016333NEI NIH HHS K12-EY016333-08NEI NIH HHS R01 EY022691NEI NIH HHS R01-EY022691
6 · The paper itself

Abstract

We propose a novel, graph-theoretic framework for distinguishing arteries from veins in a fundus image. We make use of the underlying vessel topology to better classify small and midsized vessels. We extend our previously proposed tree topology estimation framework by incorporating expert, domain-specific features to construct a simple, yet powerful global likelihood model. We efficiently maximize this model by iteratively exploring the space of possible solutions consistent with the projected vessels. We tested our method on four retinal datasets and achieved classification accuracies of 91.0%, 93.5%, 91.7%, and 90.9%, outperforming existing methods. Our results show the effectiveness of our approach, which is capable of analyzing the entire vasculature, including peripheral vessels, in wide field-of-view fundus photographs. This topology-based method is a potentially important tool for diagnosing diseases with retinal vascular manifestation.

Indexed as

AlgorithmsDatabases, FactualDiagnostic Techniques, OphthalmologicalHumansImage Processing, Computer-AssistedRetinal ArteryRetinal Vein

Identifiers

PMID26068204
PMCPMC4685460

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.