ArticleBritish dental journal2015
NICE and antibiotic prophylaxis to prevent endocarditis.
Article in British dental journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
- Long-term incidence of infective endocarditis according to the type of cardiac implantable electronic device: a nationwide comparison with moderate- and high-risk patient groups.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Article
- Comprehensive Review of Prevention and Management Strategies for Medication-related Osteonecrosis of the Jaw (MRONJ).Oral health & preventive dentistry · 2025Review
- Endocarditis prevention: time for a review of NICE guidance.The Lancet regional health. Europe · 2024Review
- Perception Regarding the NICE Guideline on Antibiotic Prophylaxis against Infective Endocarditis Following Dental Procedures: A Cross-Sectional Study.Antibiotics (Basel, Switzerland) · 2023Article
- Infective endocarditis following invasive dental procedures: IDEA case-crossover study.Health technology assessment (Winchester, England) · 2022Observational
- Evaluation of the Current Knowledge About Bacterial Endocarditis Prevention Among General Dentists in the City of Santo Domingo, Dominican Republic.Frontiers in public health · 2020Article
- Has common sense prevailed?British dental journal · 2018Article
- Antibiotic Prophylaxis of Infective Endocarditis.Current infectious disease reports · 2017Review
- Interactive clinical case: to give, or not to give, infective endocarditis prophylaxis.Heart Asia · 2017Article
- A change in the NICE guidelines on antibiotic prophylaxis.British dental journal · 2016Article
- Prophylaxis guidelines: Plea to NICE.British dental journal · 2016Article
- Odontogenic-related sepsis.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2016Article
- Prophylaxis guidelines: Repeated points.British dental journal · 2016Article
- Position statement FAQs.British dental journal · 2016Article
- Guidelines on prophylaxis to prevent infective endocarditis.British dental journal · 2016Article
- Guideline comment: Infective endocarditis.British dental journal · 2015Article
- Clinical guidance: Guidance on guidance.British dental journal · 2015Article
- Dentists' knowledge and practice regarding prevention of infective endocarditis.European journal of dentistryArticle
Corrections and comments
- Commented on by
- Commented on by
- Erratum issuedErratum.2015
Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infective endocarditis is a devastating disease with high morbidity and mortality. The link to oral bacteria has been known for many decades and has caused on going concern for dentists, patients and cardiologists. Good oral hygiene has long been advocated to prevent endocarditis. Before 2008, antibiotic prophylaxis before invasive dental procedures was also an important strategy for preventing infective endocarditis for patients at risk of the disease in the UK, and still is in most other countries of the world. In 2008, however, NICE published new guidance recommending that antibiotic prophylaxis in the UK should cease. At the time this was a highly controversial decision. New data suggests that there has been a significant increase in the incidence of infective endocarditis since the 2008 guidelines. The 2008 guidance is being reviewed and draft new guidance is being put out for public consultation. This article discusses the issues raised by the new data and the questions that should be addressed in the review and public consultation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.