Evidence map›Paper›PMID 26068056›Full record

ArticleCancer investigation2015

Quality and Outcomes of Treatment of Hypercalcemia of Malignancy.

Jason D Wright, Ana I Tergas, Cande V Ananth, William M Burke, June Y Hou, Ling Chen, Alfred I Neugut, Catherine A Richards, Dawn L Hershman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer investigation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jason D Wrighta Department of Obstetrics and Gynecology , Columbia University , New York , USA.
Ana I Tergasa Department of Obstetrics and Gynecology , Columbia University , New York , USA.
Cande V Anantha Department of Obstetrics and Gynecology , Columbia University , New York , USA.
William M Burkea Department of Obstetrics and Gynecology , Columbia University , New York , USA.
June Y Houa Department of Obstetrics and Gynecology , Columbia University , New York , USA.
Ling Chena Department of Obstetrics and Gynecology , Columbia University , New York , USA.
Alfred I Neugutb Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons , Columbia University , New York , USA.
Catherine A Richardsd Department of Epidemiology, Mailman School of Public Health , Columbia University , New York , USA .
Dawn L Hershmanb Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons , Columbia University , New York , USA.
NewYork–Presbyterian Hospital · USColumbia University · US

Funding

Training Program in Cancer-Related Population SciencesR25CA094061 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI NEUGUT, ALFRED I. · 2002 to 2016
$5.9M
The Influence of Hospital Variability on the Management of Cancer-Associated CompR01CA169121 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WRIGHT, JASON · 2013 to 2017
$1.8M
Using SWOG-Medicare database to evaluate long-term toxicities of cancer survivorsR01CA166084 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HERSHMAN, DAWN · 2013 to 2016
$1.3M
NCI NIH HHS R01 CA166084NCI NIH HHS R01 CA169121NCI NIH HHS R01-CA169121NCI NIH HHS R25 CA094061NCI NIH HHS R25 CA094061-11
6 · The paper itself

Abstract

Using a nationwide database, 4,874 patients with hypercalcemia of malignancy were identified. The in-hospital mortality rate was 6.8%. Overall, 1,971 (40.4%) patients received pamidronate and 1,399 (28.7%) received zoledronic acid during hospitalization. Calcitonin was utilized in 1,337 (27.4%) patients while glucocorticoids were administered to 1,311 (26.9%). Use of contraindicated medications was noted in 136 (2.8%) patients who received thiazide diuretics and 12 (0.2%) who received lithium. Tumor site, presence of bone metastases, and severity of illness were predictors of treatment. There was no association between treatment with bisphosphonates, calcitonin, or glucocorticoids and morbidity or mortality.

Indexed as

AgedBone NeoplasmsCalcitoninDiphosphonatesDiureticsFemaleGlucocorticoidsHumansHypercalcemiaImidazolesMaleMiddle AgedMultivariate AnalysisNeoplasmsPamidronateQuality of Health CareCalcitoninDiphosphonatesDiureticsGlucocorticoidsImidazolesPamidronateZoledronic AcidCalciumHypercalcemiaMalignancy

Identifiers

PMID26068056
PMCPMC4666677
OpenAlexW1871432574

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.