ArticleThe British journal of radiology2015
Use of multisequence 3.0-T MRI to detect severe traumatic brain injury and predict the outcome.
Article in The British journal of radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Moderate and severe traumatic brain injury: lesion frequency distribution maps and prognostic importance of brain contusions on early MRI.European radiology · 2026Article
- Association of Serum Brain-Derived Tau With Clinical Outcome and Longitudinal Change in Patients With Severe Traumatic Brain Injury.JAMA network open · 2023Article
- Clinical Features and Outcomes of Bilateral Decompression Surgery for Immediate Contralateral Hematoma after Craniectomy Following Acute Subdural Hematoma.Korean journal of neurotrauma · 2017Article
- Lesions in deep gray nuclei after severe traumatic brain injury predict neurologic outcome.PloS one · 2017Article
- Severity-Dependent Long-Term Spatial Learning-Memory Impairment in a Mouse Model of Traumatic Brain Injury.Translational stroke research · 2016Article
- Mapping the Connectome Following Traumatic Brain Injury.Current neurology and neuroscience reports · 2016Review
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Authors and funding
8 authors.
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Abstract
objectiveThe aim of this study was to evaluate multisequence 3.0-T MRI in the detection of severe traumatic brain injury (sTBI) and in predicting the outcome.
methods32 patients with sTBI were prospectively enrolled, and multisequence 3.0-T MRI was performed 4-8 weeks post injury. Quantitative data were recorded on each sequence. The ability to display the parenchymal lesions was compared with that of 64-slice spiral CT. The clinical and radiological results were correlated with the Glasgow Outcome Scale Extended scores 6 months after injury.
results3.0-T MRI could display more lesions than CT, especially when the lesion was deeply located. The lesion volumes and diffuse axonal injury (DAI) scores were different between good and poor outcome groups on fluid attenuated inversion recovery (p < 0.05). The apparent diffusion coefficient (ADC) values of the splenium of the corpus callosum and brain stem were also different (p < 0.05). Patients with unfavourable outcome showed a significantly higher volume of haemorrhage on susceptibility-weighted imaging than those with favourable outcomes and had haemorrhages generally located more deeply. Logistic regression analysis revealed that the location of haemorrhage and the ADC values of the splenium of the corpus callosum were independent risk factors for poor outcome, with an overall predictive accuracy of 91.4%.
conclusionThe joint use of conventional and advanced sequences of 3.0-T MRI can comprehensively detect the pathological changes occurring after sTBI. Haemorrhagic and non-haemorrhagic DAIs in deep structures strongly suggest poor outcome. ADVANCES IN KNOWLEDGE: This article improves the understanding of advanced MRI sequences in the detection of patients with sTBI and prediction of prognosis.
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