ArticleAsian journal of andrology
Posttesticular sperm maturation, infertility, and hypercholesterolemia.
Article in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- The Association Between Lipid Serum and Semen Parameters: a Systematic Review.Reproductive sciences (Thousand Oaks, Calif.) · 2023Pooled it
- Diagnostic classification and medical decision of idiopathic asthenozoospermia based on metabolomics analysis of seminal plasma.Journal of endocrinological investigation · 2026Article
- Article
- Effects ofAdvances in pharmacological and pharmaceutical sciences · 2026Article
- Consumption of Policosanol (RaydelPharmaceuticals (Basel, Switzerland) · 2023Article
- Serum lipid profile levels and semen quality: new insights and clinical perspectives for male infertility and men's health.International urology and nephrology · 2023Article
- Association of Overweight and Obesity with Semen Parameters and Metabolic and Hormonal Status in Young Men.Bulletin of experimental biology and medicine · 2023Article
- Multi-omics analysis reveals changes in tryptophan and cholesterol metabolism before and after sexual maturation in captive macaques.BMC genomics · 2023Article
- Lipid Signaling During Gamete Maturation.Frontiers in cell and developmental biology · 2022Review
- A Comparative Analysis of the Altered Levels of Human Seminal Plasma Constituents as Contributing Factors in Different Types of Male Infertility.Current issues in molecular biology · 2021Article
- Article
- Role of RNA N6-Methyladenosine Modification in Male Infertility and Genital System Tumors.Frontiers in cell and developmental biology · 2021Review
- Transcriptome analysis of turkey (Meleagris gallopavo) reproductive tract revealed key pathways regulating spermatogenesis and post-testicular sperm maturation.Poultry science · 2020Article
- Dependence of sperm structural and functional integrity on testicular calcineurin isoform PPP3R2 expression.Journal of molecular cell biology · 2020Article
- Low protein diet and methyl-donor supplements modify testicular physiology in mice.Reproduction (Cambridge, England) · 2020Article
- Cholesterol: A Gatekeeper of Male Fertility?Frontiers in endocrinology · 2018Review
- Article
- Manchette-acrosome disorders during spermiogenesis and low efficiency of seminiferous tubules in hypercholesterolemic rabbit model.PloS one · 2017Article
- Protective effect of resveratrol on spermatozoa function in male infertility induced by excess weight and obesity.Molecular medicine reports · 2016Article
- Study of Semen Quality, Reproductive Hormone Levels, and Lipid Levels in Men From Arkhangelsk, a City in North of European Russia.American journal of men's healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cholesterol is a key molecule in the mammalian physiology of especial particular importance for the reproductive system as it is the common precursor for steroid hormone synthesis. Cholesterol is also a recognized modulator of sperm functions, not only at the level of gametogenesis. Cholesterol homeostasis regulation is crucial for posttesticular sperm maturation, and imbalanced cholesterol levels may particularly affect these posttesticular events. Metabolic lipid disorders (dyslipidemia) affect male fertility but are most of the time studied from the angle of endocrine/testicular consequences. This review will focus on the deleterious effects of a particular dyslipidemia, i.e., hypercholesterolemia, on posttesticular maturation of mammalian spermatozoa.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.