Evidence map›Paper›PMID 26067771›Full record

ReviewHepatology international2015

The gut microbiota of nonalcoholic fatty liver disease: current methods and their interpretation.

Niels van Best, Peter L Jansen, Sander S Rensen

Open access · hybridAbstract readReview
In one paragraph

Review in Hepatology international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Gut microbiota in non-alcoholic fatty liver disease and alcohol-related liver disease: Current concepts and perspectives.Hepatology research : the official journal of the Japan Society of Hepatology · 2020
    Review
  4. Dietary fiber and chicken microbiome interaction: Where will it lead to?Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2020
    Review
  5. Function ofFrontiers in microbiology · 2020
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Frontiers in microbiology · 2017
    Article
  11. Review
  12. Review
  13. Library preparation methodology can influence genomic and functional predictions in human microbiome research.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Niels van BestDepartment of Surgery, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands.
Peter L Jansen
Sander S Rensen
Maastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of intestinal bacteria in the pathogenesis of nonalcoholic fatty liver disease is increasingly acknowledged. Recently developed microbial profiling techniques are beginning to shed light on the nature of gut microbiota alterations in nonalcoholic fatty liver disease. In this review, we summarize the gut microbiota composition changes that have been reported during different stages of human nonalcoholic fatty liver disease, and highlight the relation between bile acids and gut bacteria in this context. In addition, we discuss the different methodologies used in microbiota analyses as well as the interpretation of microbiota data. Whereas the currently available studies have provided useful information, future large-scale prospective studies with carefully phenotyped subjects and sequential sampling will be required to demonstrate a causal role of gut microbiota changes in the etiology of nonalcoholic fatty liver disease.

Indexed as

AnimalsBile Acids and SaltsFatty LiverGastrointestinal MicrobiomeHumansLiver CirrhosisNon-alcoholic Fatty Liver DiseaseBile Acids and Salts

Identifiers

PMID26067771
PMCPMC4473019
OpenAlexW561124343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.