Evidence map›Paper›PMID 26067714›Full record

ArticleScientific reports2015

Statistical iterative reconstruction algorithm for X-ray phase-contrast CT.

Dieter Hahn, Pierre Thibault, Andreas Fehringer, Martin Bech, Thomas Koehler, Franz Pfeiffer, Peter B Noël

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 46 citations in OpenAlex.

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  15. Improved reconstruction of phase-stepping data for Talbot-Lau x-ray imaging.Journal of medical imaging (Bellingham, Wash.) · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Dieter HahnChair for Biomedical Physics and Institute for Medical Engineering, Technische Universität München, Munich, Germany.
Pierre ThibaultDepartment of Physics and Astronomy, University College London, United Kingdom.
Andreas FehringerChair for Biomedical Physics and Institute for Medical Engineering, Technische Universität München, Munich, Germany.
Martin BechMedical Radiation Physics, Lund University, Lund, Sweden.
Thomas Koehler1] Philips Technologie GmbH, Innovative Technologies, Hamburg, Germany [2] Institute for Advanced Study, Technische Universität München, Munich, Germany.
Franz PfeifferChair for Biomedical Physics and Institute for Medical Engineering, Technische Universität München, Munich, Germany.
Peter B NoëlDepartment of Radiology, Technische Universität München, Munich, Germany.
Technical University of Munich · DELund University · SEUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Grating-based phase-contrast computed tomography (PCCT) is a promising imaging tool on the horizon for pre-clinical and clinical applications. Until now PCCT has been plagued by strong artifacts when dense materials like bones are present. In this paper, we present a new statistical iterative reconstruction algorithm which overcomes this limitation. It makes use of the fact that an X-ray interferometer provides a conventional absorption as well as a dark-field signal in addition to the phase-contrast signal. The method is based on a statistical iterative reconstruction algorithm utilizing maximum-a-posteriori principles and integrating the statistical properties of the raw data as well as information of dense objects gained from the absorption signal. Reconstruction of a pre-clinical mouse scan illustrates that artifacts caused by bones are significantly reduced and image quality is improved when employing our approach. Especially small structures, which are usually lost because of streaks, are recovered in our results. In comparison with the current state-of-the-art algorithms our approach provides significantly improved image quality with respect to quantitative and qualitative results. In summary, we expect that our new statistical iterative reconstruction method to increase the general usability of PCCT imaging for medical diagnosis apart from applications focused solely on soft tissue visualization.

Indexed as

AlgorithmsModels, TheoreticalAnimalsImage Processing, Computer-AssistedMiceTomography, X-Ray Computed

Identifiers

PMID26067714
PMCPMC4464273
OpenAlexW1734703104

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.