Evidence map›Paper›PMID 26067467›Full record

ArticleCritical care (London, England)2015

Is critical care ready for an economic surrogate endpoint?

M Elizabeth Wilcox, Gordon D Rubenfeld

Abstract readComment
In one paragraph

Article in Critical care (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Understanding Costs When Seeking Value in Critical Care.Annals of the American Thoracic Society · 2015
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

M Elizabeth WilcoxDepartment of Medicine, University Health Network, Toronto Western Hospital, 399 Bathurst Street, Room 411M 2nd Floor McLaughlin Wing, Toronto, ON, M5T 2S8, Canada. elizabeth.wilcox@utoronto.ca.
Gordon D RubenfeldInterdepartmental Division of Critical Care, University of Toronto, 2075 Bayview Avenue, Room D503, Toronto, ON, M4N 3M5, Canada. gordon.rubenfeld@sunnybrook.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intensive care is expensive, and thus a body of research has focused on strategies to reduce its costs. However, efforts to reduce the total cost of intensive care have met with limited success, partly because of the challenges of calculating how much a day in the ICU actually costs. We discuss these challenges and introduce the concept of total cost savings as an outcome of critical care trials, assuming statistically negative effects on mortality and quality of life.

Indexed as

DexmedetomidineHospitalizationHumansHypnotics and SedativesMidazolamProcedural SedationPropofolDexmedetomidineHypnotics and SedativesMidazolamPropofol

Identifiers

PMID26067467
PMCPMC4464123

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.