Trial reportThe Journal of neuropsychiatry and clinical neurosciences2015
Preliminary Findings Supporting Insula Metabolic Activity as a Predictor of Outcome to Psychotherapy and Medication Treatments for Depression.
Trial report in The Journal of neuropsychiatry and clinical neurosciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Defining biotypes for depression and anxiety based on large-scale circuit dysfunction: a theoretical review of the evidence and future directions for clinical translation.Depression and anxiety · 2017Pooled it
- Benefits of Sequentially Adding Cognitive-Behavioral Therapy or Antidepressant Medication for Adults With Nonremitting Depression.The American journal of psychiatry · 2019Trial
- Effects of Patient Preferences on Outcomes in the Predictors of Remission in Depression to Individual and Combined Treatments (PReDICT) Study.The American journal of psychiatry · 2017Trial
- Functional Connectivity of the Subcallosal Cingulate Cortex And Differential Outcomes to Treatment With Cognitive-Behavioral Therapy or Antidepressant Medication for Major Depressive Disorder.The American journal of psychiatry · 2017Trial
- What can the psychoneuroimmunology of yoga teach us about depression's psychopathology?Brain, behavior, & immunity - health · 2024Article
- The Role of Subgenual Resting-State Connectivity Networks in Predicting Prognosis in Major Depressive Disorder.Biological psychiatry global open science · 2024Article
- Metabolic Covariance Connectivity of Posterior Cingulate Cortex Associated with Depression Symptomatology Level in Healthy Young Adults.Metabolites · 2023Article
- Association between startle reactivity to uncertain threats and structural brain volume.Psychophysiology · 2022Article
- Mapping Neural Circuit Biotypes to Symptoms and Behavioral Dimensions of Depression and Anxiety.Biological psychiatry · 2022Article
- Establishing Evidence for Clinical Utility of a Neuroimaging Biomarker in Major Depressive Disorder: Prospective Testing and Implementation Challenges.Biological psychiatry · 2021Article
- Single and repeated ketamine treatment induces perfusion changes in sensory and limbic networks in major depressive disorder.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2020Article
- Network Changes in Insula and Amygdala Connectivity Accompany Implicit Suicidal Associations.Frontiers in psychiatry · 2020Article
- Progress in psychoradiology, the clinical application of psychiatric neuroimaging.The British journal of radiology · 2019Review
- The Impact of Whole Brain Global Functional Connectivity Density Following MECT in Major Depression: A Follow-Up Study.Frontiers in psychiatry · 2019Article
- Response rate profiles for major depressive disorder: Characterizing early response and longitudinal nonresponse.Depression and anxiety · 2018Article
- Treatment resistant depression: A multi-scale, systems biology approach.Neuroscience and biobehavioral reviews · 2018Review
- Multidimensional prediction of treatment response to antidepressants with cognitive control and functional MRI.Brain : a journal of neurology · 2017Article
- Brain 18F-FDG PET/CT findings in a case of genetic Creutzfeldt-Jakob disease due to V203I heterozygous mutation in the PRNP gene.Journal of neurology · 2017Article
- An active inference theory of allostasis and interoception in depression.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Article
- Evidence-Based Applications of Combination Psychotherapy and Pharmacotherapy for Depression.Focus (American Psychiatric Publishing) · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
A putative right anterior insula metabolism biomarker predictive of treatment outcomes was retrospectively applied to 30 depressed psychotherapy--or escitalopram-treated nonremitters who entered combination treatment. Patients whose added treatment matched the biomarker-indicated treatment remitted more often than biomarker-mismatched patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.