ArticlePloS one2015
Effect of Carotid Artery Stenting on Cognitive Function in Patients with Internal Carotid Artery Stenosis and Cerebral Lacunar Infarction: A 3-Year Follow-Up Study in China.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- Carotid Artery Stenting Intervention to Enhance Global Brain Blood Flow and Cognition in Carotid Artery Disease: Preliminary Findings from a Prospective Follow-Up MRI Study.Medicina (Kaunas, Lithuania) · 2025Article
- Temporal changes and implications of diffusion tensor imaging metrics and cerebral white matter volume in patients undergoing carotid endarterectomy - a prospective study.Neuroradiology · 2025Article
- A nomogram for predicting adverse neurovascular events after carotid artery stenting in patients with symptomatic carotid stenosis.Frontiers in neurology · 2025Article
- Characterization and individual-level prediction of cognitive state in the first year after 'mild' stroke.PloS one · 2024Article
- Article
- Cognitive Functions after Carotid Artery Stenting-1-Year Follow-Up Study.Journal of clinical medicine · 2022Article
- Cognitive Functions in Patients after Carotid Artery Revascularization-A Narrative Review.Brain sciences · 2021Review
- Impact of carotid stenosis on cerebral hemodynamic failure and cognitive impairment progression: a narrative review.Annals of translational medicine · 2021Review
- Carotid Artery Stenting and Its Impact on Cognitive Function: A Prospective Observational Study.Neurointervention · 2020Article
- Convergence Analysis of Micro-Lesions (CAML): An approach to mapping of diffuse lesions from carotid revascularization.NeuroImage. Clinical · 2018Article
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Authors and funding
9 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesCarotid artery stenting (CAS) is an important therapeutic strategy for patients with carotid artery stenosis. However, the potential influence of CAS on cognitive function in patients with carotid artery stenosis and cerebral lacunar infarction has not been determined. This study investigated changes in cognitive function associated with CAS and the factors related to these changes.
methodsThis prospective cohort study comprised 579 Chinese patients with cerebral lacunar infarction and carotid artery stenosis for whom CAS was indicated, and a matched control group of 552 healthy individuals. Cognitive function before CAS and at scheduled intervals from 6 months to 3 years was assessed with instruments that included the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) scale. Potential factors that might affect cognitive function were analyzed via logistic regression.
resultsThe MMSE and MoCA scores of the patients before CAS were significantly lower than that of the control subjects. These scores were significantly higher 6 months after CAS and sustained or increased throughout the 3-year follow-up. Also significantly improved after CAS from baseline were scores for an alternating trail test, cube copying, clock-drawing, attention, and delayed recall in an auditory-verbal learning test. Logistic regression analyses showed that age greater than 65 y, little education, diabetes, and hypertension were independent risk factors for deteriorated MoCA scores 3 years after CAS.
conclusionCAS was associated with significantly improved cognitive function in cerebral lacunar infarction patients with severe stenosis.
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