ArticlePloS one2015
Head and Neck Veins of the Mouse. A Magnetic Resonance, Micro Computed Tomography and High Frequency Color Doppler Ultrasound Study.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 33 citations in OpenAlex.
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- Mouse Cardiovascular Imaging.Current protocols · 2024Review
- Biodistribution of PET radiotracers in tumor-bearing TRAMP mice administered by retroorbital or jugular vein injections.Scientific reports · 2024Article
- Beyond the microcirculation: sequestration of infected red blood cells and reduced flow in large draining veins in experimental cerebral malaria.Nature communications · 2024Article
- Lateral entorhinal cortex subpopulations represent experiential epochs surrounding reward.Nature neuroscience · 2024Article
- Lateral entorhinal cortex subpopulations represent experiential epochs surrounding reward.bioRxiv : the preprint server for biology · 2023Article
- Immune compartments at the brain's borders in health and neurovascular diseases.Seminars in immunopathology · 2023Review
- A chemo-mechanical cochleostomy preserves hearing for the in vivo functional imaging of cochlear cells.Nature protocols · 2023Review
- Non-contrast assessment of blood-brain barrier permeability to water in mice: An arterial spin labeling study at cerebral veins.NeuroImage · 2023Article
- State of the art in cerebral venous sinus thrombosis animal models.Journal of thrombosis and haemostasis : JTH · 2022Review
- A Novel Mouse Model for Cerebral Venous Sinus Thrombosis.Translational stroke research · 2021Article
- Tentorial venous anatomy of mice and humans.JCI insight · 2021Article
- Article
- Hypoxia ameliorates brain hyperoxia and NADMolecular genetics and metabolism · 2021Article
- Persistence and progression of staphylococcal infection in the presence of public goods.NPJ biofilms and microbiomes · 2020Article
- The pig as a preclinical traumatic brain injury model: current models, functional outcome measures, and translational detection strategies.Neural regeneration research · 2019Review
- Outflow of cerebrospinal fluid is predominantly through lymphatic vessels and is reduced in aged mice.Nature communications · 2017Article
- Correlation between volumetric oxygenation responses and electrophysiology identifies deep thalamocortical activity during epileptic seizures.Neurophotonics · 2017Article
Corrections and comments
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Authors and funding
11 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To characterize the anatomy of the venous outflow of the mouse brain using different imaging techniques. Ten C57/black male mice (age range: 7-8 weeks) were imaged with high-frequency Ultrasound, Magnetic Resonance Angiography and ex-vivo Microcomputed tomography of the head and neck. Under general anesthesia, Ultrasound of neck veins was performed with a 20 MHz transducer; head and neck Magnetic Resonance Angiography data were collected on 9.4 T or 7 T scanners, and ex-vivo Microcomputed tomography angiography was obtained by filling the vessels with a radiopaque inert silicone rubber compound. All procedures were approved by the local ethical committee. The dorsal intracranial venous system is quite similar in mice and humans. Instead, the mouse Internal Jugular Veins are tiny vessels receiving the sigmoid sinuses and tributaries from cerebellum, occipital lobe and midbrain, while the majority of the cerebral blood, i.e. from the olfactory bulbs and fronto-parietal lobes, is apparently drained through skull base connections into the External Jugular Vein. Three main intra-extracranial anastomoses, absent in humans, are: 1) the petrosquamous sinus, draining into the posterior facial vein, 2) the veins of the olfactory bulb, draining into the superficial temporal vein through a foramen of the frontal bone 3) the cavernous sinus, draining in the External Jugular Vein through a foramen of the sphenoid bone. The anatomical structure of the mouse cranial venous outflow as depicted by Ultrasound, Microcomputed tomography and Magnetic Resonance Angiography is different from humans, with multiple connections between intra- and extra-cranial veins.
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