Evidence map›Paper›PMID 26067001›Full record

ArticleSchizophrenia bulletin2015

Incorporating Sex as a Variable in Preclinical Neuropsychiatric Research.

Margaret M McCarthy

Abstract read
In one paragraph

Article in Schizophrenia bulletin, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Trial
  2. Article
  3. Neurological Effects ofNutrients · 2026
    Article
  4. Article
  5. Gender/Sex Entanglement, Structural Sexism, and Injury: The Case of Australian Rules Football.American journal of human biology : the official journal of the Human Biology Council · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. N-Acetylcysteine Alleviates Depressive-Like Behaviors in Adolescent EAAC1International journal of biological sciences · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Margaret M McCarthyDepartments of Pharmacology, Physiology and Psychiatry, University of Maryland School of Medicine, Baltimore, MD mmccarth@umaryland.edu.

Funding

Neuroinflammation, Epigenetics and Male VulnerabilityR01MH052716 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI MARGARET M. MCCARTHY · 2000 to 2026
$9.6M
Prostaglandins and Cerebellum DevelopmentR01MH091424 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI MCCARTHY, MARGARET M. · 2010 to 2020
$3.8M
Estradiol and Hippocampal DevelopmentR01NS050525 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI MCCARTHY, MARGARET M. · 2005 to 2013
$2.9M
NIMH NIH HHS R01MH091424NIMH NIH HHS R01MH52716NINDS NIH HHS R01NS050525
6 · The paper itself

Abstract

In an effort to increase applicability of preclinical research to both men and women, the National Institute of Health is anticipated to put forth guidelines for the incorporation of sex as a variable in animal studies. Common myths and perceived barriers to the inclusion of females in neuroscience research are discussed and a roadmap for implementation provided. Accounting for sex as a variable does not require studying sex differences and is easier to implement than generally assumed.

Indexed as

Models, AnimalSex CharacteristicsAnimalsBiomedical ResearchFemaleMaleResearch DesignSex Factorsbehaviorhormonessex differences

Identifiers

PMID26067001
PMCPMC4535645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.