Evidence map›Paper›PMID 26066966›Full record

ArticleAmerican journal of public health2015

Environmental Influences on HIV Medication Adherence: The Role of Neighborhood Disorder.

Hilary L Surratt, Steven P Kurtz, Maria A Levi-Minzi, Minxing Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 4 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 4 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Systematic Review of Neighborhood Factors Impacting HIV Care Continuum Participation in the United States.Journal of urban health : bulletin of the New York Academy of Medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hilary L SurrattHilary L. Surratt, Steven P. Kurtz, and Maria A. Levi-Minzi are with the Center for Applied Research on Substance Use and Health Disparities, Nova Southeastern University, Fort Lauderdale, FL. Minxing Chen is with the Department of Biostatistics, MD Anderson Cancer Center, University of Texas, Houston.
Steven P KurtzHilary L. Surratt, Steven P. Kurtz, and Maria A. Levi-Minzi are with the Center for Applied Research on Substance Use and Health Disparities, Nova Southeastern University, Fort Lauderdale, FL. Minxing Chen is with the Department of Biostatistics, MD Anderson Cancer Center, University of Texas, Houston.
Maria A Levi-MinziHilary L. Surratt, Steven P. Kurtz, and Maria A. Levi-Minzi are with the Center for Applied Research on Substance Use and Health Disparities, Nova Southeastern University, Fort Lauderdale, FL. Minxing Chen is with the Department of Biostatistics, MD Anderson Cancer Center, University of Texas, Houston.
Minxing ChenHilary L. Surratt, Steven P. Kurtz, and Maria A. Levi-Minzi are with the Center for Applied Research on Substance Use and Health Disparities, Nova Southeastern University, Fort Lauderdale, FL. Minxing Chen is with the Department of Biostatistics, MD Anderson Cancer Center, University of Texas, Houston.
Nova Southeastern University · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
The Diversion of Antiretroviral Medications to Street MarketsR01DA023157 · NIDA · UNIVERSITY OF DELAWARE · PI SURRATT, HILARY L · 2009 to 2012
$1.7M
NIDA NIH HHS R01 DA023157NIDA NIH HHS R01DA023157
6 · The paper itself

Abstract

objectivesWe hypothesized that highly disordered neighborhoods would expose residents to environmental pressures, leading to reduced antiretroviral (ARV) medication adherence.

methodsUsing targeted sampling, we enrolled 503 socioeconomically disadvantaged HIV-positive substance users in urban South Florida between 2010 and 2012. Participants completed a 1-time standardized interview that took approximately 1 hour. We tested a multiple mediation model to examine the direct and indirect effects of neighborhood disorder on diversion-related nonadherence to ARVs; risky social networks and housing instability were examined as mediators of the disordered neighborhood environment.

resultsThe total indirect effect in the model was statistically significant (P = .001), and the proportion of the total effect mediated was 53%. The model indicated substantial influence of neighborhood disorder on nonadherence to ARVs, operating through recent homelessness and diverter network size.

conclusionsLong-term improvements in diversion-related ARV adherence will require initiatives to reduce demand for illicit ARV medications, as well as measures to reduce patient vulnerability to diversion, including increased resources for accessible housing, intensive treatment, and support services.

Indexed as

Drug MonitoringAnti-HIV AgentsFemaleFloridaHIV InfectionsHumansInterviews as TopicMaleMedication AdherenceMiddle AgedModels, TheoreticalResidence CharacteristicsSocial EnvironmentAnti-HIV Agents

Identifiers

PMID26066966
PMCPMC4498986
OpenAlexW2135866936

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.