ArticleAmerican journal of public health2015
Sedative Hypnotic Medication Use and the Risk of Motor Vehicle Crash.
Article in American journal of public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 69 citations in OpenAlex.
- Assessment of delta-9-tetrahydrocannabinol (THC) in saliva and blood after oral administration of medical cannabis with respect to its effect on driving abilities.Physiological research · 2022Trial
- Roles of Psychiatry, Dietary, and Oncology Services in Occupational Medicine: A Comprehensive Review.Cureus · 2025Review
- Nonbenzodiazepine hypnotics and police-reported motor vehicle crash risk among older adults: a sequential target trial emulation.American journal of epidemiology · 2025Article
- Diphenhydramine: It is time to say a final goodbye.The World Allergy Organization journal · 2025Review
- Implications of using administrative healthcare data to identify risk of motor vehicle crash-related injury: the importance of distinguishing crash from crash-related injury.Injury epidemiology · 2024Article
- Medication and Road Test Performance Among Cognitively Healthy Older Adults.JAMA network open · 2023Article
- The abuse potential of lemborexant, a dual orexin receptor antagonist, according to the 8 factors of the Controlled Substances Act.Psychopharmacology · 2023Review
- Declining trend in use of medications for sleep disturbance in the United States from 2013 to 2018.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Maintaining Implementation through Dynamic Adaptations (MIDAS): protocol for a cluster-randomized trial of implementation strategies to optimize and sustain use of evidence-based practices in Veteran Health Administration (VHA) patients.Implementation science communications · 2022Article
- Treatment of Heart Failure Patients with Anxiolytics Is Associated with Adverse Outcomes, with and without Depression.Journal of clinical medicine · 2020Article
- Beyond Prescriptions Monitoring Programs: The Importance of Having the Conversation about Benzodiazepine Use.Journal of clinical medicine · 2019Article
- Driving performance and neurocognitive skills of long-term users of benzodiazepine anxiolytics and hypnotics.Human psychopharmacology · 2019Article
- Trends in Prescribed Central Nervous System Depressant Medications Among Adults Who Regularly Consume Alcohol: United States 1999 to 2014.Alcoholism, clinical and experimental research · 2019Article
- Policies for Deprescribing: An International Scan of Intended and Unintended Outcomes of Limiting Sedative-Hypnotic Use in Community-Dwelling Older Adults.Healthcare policy = Politiques de sante · 2019Article
- Increased motor vehicle crashes following induced earthquakes in Oklahoma, USA.The Science of the total environment · 2019Article
- Patient-Oriented Policies To Reduce The Harmful Effects Of Medication On Seniors' Brain Function.The Public policy and aging report · 2018Article
- Insomnia in Elderly Patients: Recommendations for Pharmacological Management.Drugs & aging · 2018Review
- Responsiveness of Veterans Affairs Health Care System to Zolpidem Safety Warnings.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018Article
- Cognitive Decline and Older Driver Crash Risk.Journal of the American Geriatrics Society · 2018Article
- Diagnosed dementia and the risk of motor vehicle crash among older drivers.Accident; analysis and prevention · 2018Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWe sought to estimate the association between sedative hypnotic use and motor vehicle crash risk.
methodsWe conducted a new user cohort study of 409 171 adults in an integrated health care system. Health plan data were linked to driver license and collision records. Participants were aged 21 years or older, licensed to drive in Washington State, had at least 1 year of continuous enrollment between 2003 and 2008, and were followed until death, disenrollment, or study end. We used proportional hazards regression to estimate the risk of crash associated with 3 sedatives.
resultsWe found 5.8% of patients received new sedative prescriptions, with 11 197 person-years of exposure. New users of sedatives were associated with an increased risk of crash relative to nonuse: temazepam hazard ratio (HR) = 1.27 (95% confidence interval [CI] = 0.85, 1.91), trazodone HR = 1.91 (95% CI = 1.62, 2.25), and zolpidem HR = 2.20 (95% CI = 1.64, 2.95). These risk estimates are equivalent to blood alcohol concentration levels between 0.06% and 0.11%.
conclusionsNew use of sedative hypnotics is associated with increased motor vehicle crash risk. Clinicians initiating sedative hypnotic treatment should consider length of treatment and counseling on driving risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.