Evidence map›Paper›PMID 26066625›Full record

ArticleAJNR. American journal of neuroradiology2015

Dynamic Angiography and Perfusion Imaging Using Flat Detector CT in the Angiography Suite: A Pilot Study in Patients with Acute Middle Cerebral Artery Occlusions.

T Struffert, Y Deuerling-Zheng, S Kloska, T Engelhorn, S Lang, A Mennecke, M Manhart, C M Strother, S Schwab, A Doerfler

Open access · hybridAbstract readClinical StudyComparative Study
In one paragraph

Article in AJNR. American journal of neuroradiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  5. Direct to hybrid CT-angiosuite (Nexaris) reduces treatment time for stroke thrombectomy (Direct-ST): A prospective simulation study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
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  14. Angiography suite cone-beam CT perfusion for selection of thrombectomy patients: A pilot study.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022
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  17. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

T StruffertFrom the Department of Neuroradiology (T.S., S.K., T.E., S.L., A.M., M.M., A.D.) tobias.struffert@uk-erlangen.de.
Y Deuerling-ZhengSiemens AG, Healthcare Sector (Y.D.-Z.), Forchheim, Germany.
S KloskaFrom the Department of Neuroradiology (T.S., S.K., T.E., S.L., A.M., M.M., A.D.).
T EngelhornFrom the Department of Neuroradiology (T.S., S.K., T.E., S.L., A.M., M.M., A.D.).
S LangFrom the Department of Neuroradiology (T.S., S.K., T.E., S.L., A.M., M.M., A.D.).
A MenneckeFrom the Department of Neuroradiology (T.S., S.K., T.E., S.L., A.M., M.M., A.D.).
M ManhartFrom the Department of Neuroradiology (T.S., S.K., T.E., S.L., A.M., M.M., A.D.) Pattern Recognition Lab (M.M.).
C M StrotherDepartment of Radiology (C.M.S.), University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
S SchwabDepartment of Neurology (S.S.), University of Erlangen-Nuremberg, Erlangen, Germany.
A DoerflerFrom the Department of Neuroradiology (T.S., S.K., T.E., S.L., A.M., M.M., A.D.).
Friedrich-Alexander-Universität Erlangen-Nürnberg · DESiemens (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposePerfusion and angiographic imaging using intravenous contrast application to evaluate stroke patients is now technically feasible by flat detector CT performed by the angiographic system. The aim of this pilot study was to show the feasibility and qualitative comparability of a novel flat detector CT dynamic perfusion and angiographic imaging protocol in comparison with a multimodal stroke MR imaging protocol. MATERIALS AND

methodsIn 12 patients with acute stroke, MR imaging and the novel flat detector CT protocol were performed before endovascular treatment. Perfusion parameter maps (MTT, TTP, CBV, CBF) and MIP/volume-rendering technique images obtained by using both modalities (MR imaging and flat detector CT) were compared.

resultsComparison of MIP/volume-rendering technique images demonstrated equivalent visibility of the occlusion site. Qualitative comparison of perfusion parameter maps by using ASPECTS revealed high Pearson correlation coefficients for parameters CBF, MTT, and TTP (0.95-0.98), while for CBV, the coefficient was lower (0.49).

conclusionsWe have shown the feasibility of a novel dynamic flat detector CT perfusion and angiographic protocol for the diagnosis and triage of patients with acute ischemic stroke. In a qualitative comparison, the parameter maps and MIP/volume-rendering technique images compared well with MR imaging. In our opinion, this flat detector CT application may substitute for multisection CT imaging in selected patients with acute stroke so that in the future, patients with acute stroke may be directly referred to the angiography suite, thereby avoiding transportation and saving time.

Indexed as

AdultAgedAged, 80 and overCerebral AngiographyFeasibility StudiesFemaleHumansImage Processing, Computer-AssistedInfarction, Middle Cerebral ArteryMagnetic Resonance AngiographyMaleMiddle AgedPerfusion ImagingPilot ProjectsSensitivity and SpecificityTomography, X-Ray Computed

Identifiers

PMID26066625
PMCPMC7965022
OpenAlexW1867469610

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.