Evidence map›Paper›PMID 26066472›Full record

ReviewCurrent opinion in nephrology and hypertension2015

Current MRI techniques for the assessment of renal disease.

Takamune Takahashi, Feng Wang, Christopher C Quarles

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in nephrology and hypertension, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Takamune TakahashiaDivision of Nephrology and Hypertension bDepartment of Radiology and Radiological Sciences cVanderbilt University Institute of Imaging Science, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Feng Wang
Christopher C Quarles
Vanderbilt University · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
The Role of the EGF Receptor in Acute and Chronic Renal InjuryR01DK051265 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RAYMOND C. HARRIS, Mingzhi Zhang · 1997 to 2026
$10.1M
Vanderbilt O'Brien Mouse Kidney Physiology and Disease CenterP30DK079341 · NIDDK · VANDERBILT UNIVERSITY · PI HARRIS, RAYMOND C. · 2008 to 2013
$4.4M
NCI NIH HHS CA68485NCI NIH HHS P30 CA068485NIDDK NIH HHS DK79341NIDDK NIH HHS P30 DK079341NIDDK NIH HHS R01 DK051265
6 · The paper itself

Abstract

purpose of reviewOver the past decade, a variety of MRI methods have been developed and applied to many kidney diseases. These MRI techniques show great promise, enabling the noninvasive assessment of renal structure, function and injury in individuals. This review will highlight the current applications of functional MRI techniques for the assessment of renal disease and discuss future directions. RECENT

findingsMany pathological (functional and structural) changes or factors in renal disease can be assessed by advanced MRI techniques. These include renal vascular structure and function (contrast-enhanced MRI, arterial spin labelling), tissue oxygenation (blood oxygen level dependent MRI), renal tissue injury and fibrosis (diffusion or magnetization transfer imaging, magnetic resonance elastography), renal metabolism (chemical exchange saturation transfer, spectroscopic imaging), nephron endowment (cationic-contrast imaging), sodium concentration (23Na-MRI) and molecular events (targeted-contrast imaging). SUMMARY: Current advances in MRI techniques have enabled the noninvasive investigation of renal disease. Further development, evaluation and application of the MRI techniques should facilitate better understanding and assessment of renal disease, and the development of new imaging biomarkers, enabling the intensified treatment of high-risk populations and a more rapid interrogation of novel therapeutic agents and protocols.

Indexed as

Magnetic Resonance ImagingAnimalsHumansKidneyKidney DiseasesOxygen ConsumptionRenal CirculationRisk Assessment

Identifiers

PMID26066472
PMCPMC4467464
OpenAlexW1997013024

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.