ReviewCurrent opinion in microbiology2015
Halophiles and their enzymes: negativity put to good use.
Review in Current opinion in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
128 citing papers in PubMed, 306 citations in OpenAlex.
- Biotechnological assessment of a halotolerant bacillaceae from west province of Mazandaran as a Novel source of extracellular proteases.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Ecological and evolutionary implications of a mobile genetic element-rich haloarchaeon with unique osmotic resilience.Microbiology spectrum · 2026Article
- Unveiling the influence of salt concentration on the different stages of the catalytic cycle of a halophilic enzyme.The FEBS journal · 2026Article
- A Novel Polyphosphate-Degrading Enzyme Confers Growth on Exogenous Polyphosphate in the Archaeon Haloferax volcanii.Environmental microbiology · 2026Article
- Biochemical characterization of chitinolytic Bacillus isolates from a hypersaline wetland and their biopriming potential for improving wheat germination under salinity stress.BMC plant biology · 2026Article
- Comparative metagenomic analysis of microbial communities: unravelling microbial communities from the great Rann of Kachchh and coastal saltpans, Gujarat, India.Extremophiles : life under extreme conditions · 2026Article
- The Expanding Histone Universe: Histone-Based DNA Organization in Noneukaryotic Organisms.Annual review of biophysics · 2026Review
- Lignocellulose-mediated selection of potential halophilic PET-degrading enzymes from mangrove soil.Nature communications · 2026Article
- A New Era for Using Natural Pigments: The Case of the CBiotechnology and applied biochemistry · 2026Review
- Recent Advances in Understanding Bio-Compounds from Haloarchaea.Journal of microbiology and biotechnology · 2026Review
- Article
- Recombinant Expression and Characterization of a New Endogenous and Halophilic GH13_5 Subfamily α-Amylase from Paenibacillus pabuli.Applied biochemistry and biotechnology · 2026Article
- Exploring Marinilactibacillus sp from Lake Urmia as a novel halophilic source of antibacterial bioactive compounds.Extremophiles : life under extreme conditions · 2026Article
- Identification and Cultivation of Biotechnologically Relevant Microalgal and Cyanobacterial Species Isolated from Sečovlje Salt Pans, Slovenia.Marine drugs · 2026Article
- Virgibacillus aidingensis sp. nov., a bacterium isolated from a hypersaline sediment in Xinjiang Province, North-west China.Antonie van Leeuwenhoek · 2026Article
- Hydrostatic pressure-enabled transformation inFrontiers in microbiology · 2026Article
- Extremophilic bacteriorhodopsin from hypersaline salt pan: characterization and photoelectrochemical assessment for potential biosensor applications.Frontiers in microbiology · 2026Article
- Genome sequence and methylome of the extremely halophilic bacteriumMicrobiology resource announcements · 2025Article
- Xylan Degradation in the Halotolerant BacteriumJournal of agricultural and food chemistry · 2025Article
- Enhancing stability of enzymes for industrial applications: molecular insights and emerging approaches.World journal of microbiology & biotechnology · 2025Review
68 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Halophilic microorganisms possess stable enzymes that function in very high salinity, an extreme condition that leads to denaturation, aggregation, and precipitation of most other proteins. Genomic and structural analyses have established that the enzymes of halophilic Archaea and many halophilic Bacteria are negatively charged due to an excess of acidic over basic residues, and altered hydrophobicity, which enhance solubility and promote function in low water activity conditions. Here, we provide an update on recent bioinformatic analysis of predicted halophilic proteomes as well as experimental molecular studies on individual halophilic enzymes. Recent efforts on discovery and utilization of halophiles and their enzymes for biotechnology, including biofuel applications are also considered.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.