Evidence map›Paper›PMID 26066173›Full record

ArticlePhysical review. E, Statistical, nonlinear, and soft matter physics2015

Composite generalized Langevin equation for Brownian motion in different hydrodynamic and adhesion regimes.

Hsiu-Yu Yu, David M Eckmann, Portonovo S Ayyaswamy, Ravi Radhakrishnan

Abstract read
In one paragraph

Article in Physical review. E, Statistical, nonlinear, and soft matter physics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Evolution of Multivalent Nanoparticle Adhesion via Specific Molecular Interactions.Langmuir : the ACS journal of surfaces and colloids · 2016
    Article
  8. Effect of wall-mediated hydrodynamic fluctuations on the kinetics of a Brownian nanoparticle.Proceedings. Mathematical, physical, and engineering sciences · 2016
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hsiu-Yu YuDepartment of Chemical and Biomolecular Engineering and Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
David M EckmannDepartment of Anesthesiology and Critical Care and Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Portonovo S AyyaswamyDepartment of Mechanical Engineering and Applied Mechanics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Ravi RadhakrishnanDepartment of Bioengineering and Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

Funding

Targeted Microcarrier Design and OptimizationR01EB006818 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI ECKMANN, DAVID M · 2008 to 2016
$3.3M
Bridging multiple scales in modeling targeted drug nanocarrier deliveryU01EB016027 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI ECKMANN, DAVID M, RADHAKRISHNAN, RAVI · 2013 to 2017
$2.7M
NIBIB NIH HHS R01 EB006818NIBIB NIH HHS U01 EB016027
6 · The paper itself

Abstract

We present a composite generalized Langevin equation as a unified framework for bridging the hydrodynamic, Brownian, and adhesive spring forces associated with a nanoparticle at different positions from a wall, namely, a bulklike regime, a near-wall regime, and a lubrication regime. The particle velocity autocorrelation function dictates the dynamical interplay between the aforementioned forces, and our proposed methodology successfully captures the well-known hydrodynamic long-time tail with context-dependent scaling exponents and oscillatory behavior due to the binding interaction. Employing the reactive flux formalism, we analyze the effect of hydrodynamic variables on the particle trajectory and characterize the transient kinetics of a particle crossing a predefined milestone. The results suggest that both wall-hydrodynamic interactions and adhesion strength impact the particle kinetics.

Indexed as

HydrodynamicsModels, TheoreticalMotionNanoparticlesAdhesivenessKineticsStochastic Processes

Identifiers

PMID26066173
PMCPMC4467459

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.