Trial reportChest2015
Lung Function in Rural Guatemalan Women Before and After a Chimney Stove Intervention to Reduce Wood Smoke Exposure: Results From the Randomized Exposure Study of Pollution Indoors and Respiratory Effects and Chronic Respiratory Effects of Early Childhood Exposure to Respirable Particulate Matter Study.
Trial report in Chest, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 30 citations in OpenAlex.
- Household Air Pollution Interventions to Improve Health in Low- and Middle-Income Countries: An Official American Thoracic Society Research Statement.American journal of respiratory and critical care medicine · 2024Article
- The Conundrum of Cleaner Cookstove Interventions: Necessary but Insufficient?American journal of respiratory and critical care medicine · 2021Article
- Personal strategies to minimise effects of air pollution on respiratory health: advice for providers, patients and the public.The European respiratory journal · 2020Article
- Exposure to household air pollution from biomass cookstoves and self-reported symptoms among women in rural Honduras.International journal of environmental health research · 2020Article
- Positive impact of improved cookstove usage on respiratory health in Congolese refugees: a prospective cohort study.Environmental science and pollution research international · 2020Article
- Respiratory Symptoms and Lung Function among Ethiopian Women in Relation to Household Fuel Use.International journal of environmental research and public health · 2019Article
- Innate Lymphoid Cell-Dependent Airway Epithelial and Inflammatory Responses to Inhaled Ozone: A New Paradigm in Pathogenesis.Toxicologic pathology · 2019Review
- COPD's early origins in low-and-middle income countries: what are the implications of a false start?NPJ primary care respiratory medicine · 2019Article
- Environmental exposures and systemic hypertension are risk factors for decline in lung function.Thorax · 2018Article
- Airflow Obstruction and Use of Solid Fuels for Cooking or Heating: BOLD Results.American journal of respiratory and critical care medicine · 2018Article
- Oxidative Stress in the Lung - The Essential Paradox.Current opinion in toxicology · 2018Article
- Nasopharyngeal Pneumococcal Density Is Associated With Viral Activity but Not With Use of Improved Stoves Among Young Andean Children.Open forum infectious diseases · 2017Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundCOPD is the third most frequent cause of death globally, with much of this burden attributable to household biomass smoke exposure in developing countries. As biomass smoke exposure is also associated with cardiovascular disease, lower respiratory infection, lung cancer, and cataracts, it presents an important target for public health intervention.
methodsLung function in Guatemalan women exposed to wood smoke from open fires was measured throughout the Randomized Exposure Study of Pollution Indoors and Respiratory Effects (RESPIRE) stove intervention trial and continued during the Chronic Respiratory Effects of Early Childhood Exposure to Respirable Particulate Matter (CRECER) cohort study. In RESPIRE, early stove households received a chimney woodstove at the beginning of the 18-month trial, and delayed stove households received a stove at trial completion. Personal exposure to wood smoke was assessed with exhaled breath carbon monoxide (CO) and personal CO tubes. Change in lung function between intervention groups and as a function of wood smoke exposure was assessed using random effects models.
resultsOf 306 women participating in both studies, acceptable spirometry was collected in 129 early stove and 136 delayed stove households (n = 265), with a mean follow-up of 5.6 years. Despite reduced wood smoke exposures in early stove households, there were no significant differences in any of the measured spirometric variables during the study period (FEV1, FVC, FEV1/FVC ratio, and annual change) after adjustment for confounding.
conclusionsIn these young Guatemalan women, there was no association between lung function and early randomization to a chimney stove or personal wood smoke exposure. Future stove intervention trials should incorporate cleaner stoves, longer follow-up, or potentially susceptible groups to identify meaningful differences in lung function.
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