Evidence map›Paper›PMID 26065414›Full record

ArticleParasites & vectors2015

Taenia solium taeniosis/cysticercosis and the co-distribution with schistosomiasis in Africa.

Uffe Christian Braae, Christopher F L Saarnak, Samson Mukaratirwa, Brecht Devleesschauwer, Pascal Magnussen, Maria Vang Johansen

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06376396 (Assessment of Combined Antiparasitic Drugs Praziquantel and Albendazole Versus Albendazole Alone in the Treatment of Active Parenchymal Neurocysticercosis in Tanzania and Zambia), which is not on this map. Cited by 36 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 3 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06376396 phase4not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Assessment of Combined Antiparasitic Drugs Praziquantel and Albendazole Versus Albendazole Alone in the Treatment of Active Parenchymal Neurocysticercosis in Tanzania and Zambia

TypeinterventionalSponsorR-Evolution Worldwide S.r.l. Impresa SocialeRan2024 to 2026Enrolled300ConditionsNeurocysticercosisArmsalbendazole and praziquantel, Albendazole
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Article
  7. Article
  8. Spatial and Temporal Changes inVeterinary medicine international · 2024
    Article
  9. Article
  10. A Spatial Autocorrelation Method forTropical medicine and infectious disease · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Seroprevalence ofBioMed research international · 2021
    Article
  17. Review
  18. Evidence for Transmission ofFrontiers in veterinary science · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Uffe Christian BraaeDepartment of Veterinary Disease Biology, Section for Parasitology and Aquatic Diseases, Faculty of Health and Medical Sciences, University of Copenhagen, DK-1870, Frederiksberg, Denmark. braae@sund.ku.dk.
Christopher F L SaarnakDepartment of Veterinary Disease Biology, Section for Parasitology and Aquatic Diseases, Faculty of Health and Medical Sciences, University of Copenhagen, DK-1870, Frederiksberg, Denmark. cls@sund.ku.dk.
Samson MukaratirwaSchool of Life Sciences, University of KwaZulu-Natal, Durban, South Africa. mukaratirwa@ukzn.ac.za.
Brecht DevleesschauwerDepartment of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, 9820, Merelbeke, Belgium. brechtdv@gmail.com.
Pascal MagnussenDepartment of Veterinary Disease Biology, Section for Parasitology and Aquatic Diseases, Faculty of Health and Medical Sciences, University of Copenhagen, DK-1870, Frederiksberg, Denmark. pma@sund.ku.dk.
Maria Vang JohansenDepartment of Veterinary Disease Biology, Section for Parasitology and Aquatic Diseases, Faculty of Health and Medical Sciences, University of Copenhagen, DK-1870, Frederiksberg, Denmark. mvj@sund.ku.dk.
University of Copenhagen · DKGhent University · BEUniversity of KwaZulu-Natal · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to map the distribution of Taenia solium taeniosis/cysticercosis and the co-distribution with schistosomiasis in Africa. These two major neglected tropical diseases are presumed to be widely distributed in Africa, but currently the level of co-distribution is unclear.

methodsA literature search on T. solium taeniosis/cysticercosis was performed to compile all known studies on the presence of T. solium and apparent prevalence of taeniosis and porcine cysticercosis in Africa. Studies were geo-referenced using an online gazetteer. A Bayesian framework was used to combine the epidemiological data on the apparent prevalence with external information on test characteristics to estimate informed district-level prevalence of taeniosis and porcine cysticercosis. Districts with T. solium taeniosis/cysticercosis presence were cross-referenced with the Global Neglected Tropical Diseases Database for schistosomiasis presence.

resultsThe search strategies identified 141 reports of T. solium in Africa from 1985 to 2014 from a total of 476 districts in 29 countries, 20 with porcine cysticercosis, 22 with human cysticercosis, and 16 with taeniosis, in addition to 2 countries identified from OIE reports. All 31 countries were considered, on national scale, to have co-distribution with schistosomiasis. Presence of both parasites was confirmed in 124 districts in 17 countries. The informed prevalence of taeniosis and porcine cysticercosis were estimated for 14 and 41 districts in 10 and 13 countries, respectively.

conclusionsWith the paucity of data, T. solium infection is grossly under-reported and expected to be more widespread than this study suggests. In areas where co-distribution occurs there is a need for increased emphasis on evaluation of integrated intervention approaches for these two helminth infections and allocation of resources for evaluating the extent of adverse effects caused by mass drug administration.

Indexed as

AfricaAnimalsCoinfectionCysticercosisCysticercusSchistosomaSchistosomiasisSwineSwine DiseasesTaeniasisTaenia solium

Identifiers

PMID26065414
PMCPMC4465723
OpenAlexW1583552270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.