Evidence map›Paper›PMID 26065397›Full record

ArticleEuropean radiology2016

Magnetization transfer imaging of normal and abnormal testis: preliminary results.

Athina C Tsili, Alexandra Ntorkou, Dimitrios Baltogiannis, Anastasios Sylakos, Sotirios Stavrou, Loukas G Astrakas, Vasilios Maliakas, Nikolaos Sofikitis, Maria I Argyropoulou

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Sonographically indeterminate scrotal masses: how MRI helps in characterization.Diagnostic and interventional radiology (Ankara, Turkey) · 2018
    Review
  5. Imaging of the scrotum: beyond sonography.Insights into imaging · 2018
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Athina C TsiliDepartment of Clinical Radiology, Medical School, University of Ioannina, 45110, Ioannina, Greece. a_tsili@yahoo.gr.
Alexandra NtorkouDepartment of Clinical Radiology, Medical School, University of Ioannina, 45110, Ioannina, Greece. alexdorkou@hotmail.com.
Dimitrios BaltogiannisDepartment of Urology, Medical School, University of Ioannina, 45110, Ioannina, Greece. dbaltog@cc.uoi.gr.
Anastasios SylakosDepartment of Urology, Medical School, University of Ioannina, 45110, Ioannina, Greece. anasylakos@yahoo.gr.
Sotirios StavrouDepartment of Urology, Medical School, University of Ioannina, 45110, Ioannina, Greece. s.sotiris@yahoo.com.
Loukas G AstrakasDepartment of Medical Physics, Medical School, University of Ioannina, 45110, Ioannina, Greece. astrakas@uoi.gr.
Vasilios MaliakasDepartment of Clinical Radiology, Medical School, University of Ioannina, 45110, Ioannina, Greece. vmaliax@gmail.com.
Nikolaos SofikitisDepartment of Urology, Medical School, University of Ioannina, 45110, Ioannina, Greece. akrosnin@hotmail.com.
Maria I ArgyropoulouDepartment of Clinical Radiology, Medical School, University of Ioannina, 45110, Ioannina, Greece. margyrop@cc.uoi.gr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim was to determine the magnetization transfer ratio (MTR) of normal testes, possible variations with age and to assess the feasibility of MTR in characterizing various testicular lesions.

methodsEighty-six men were included. A three-dimensional gradient-echo MT sequence was performed, with/without an on-resonance binomial prepulse. MTR was calculated as: (SIo-SIm)/(SIo) × 100 %, where SIm and SIo refers to signal intensities with and without the saturation pulse, respectively. Subjects were classified as: group 1, 20-39 years; group 2, 40-65 years; and group 3, older than 65 years of age. Analysis of variance (ANOVA) followed by the least significant difference test was used to assess variations of MTR with age. Comparison between the MTR of normal testis, malignant and benign testicular lesions was performed using independent-samples t testing.

resultsANOVA revealed differences of MTR between age groups (F = 7.51, P = 0.001). Significant differences between groups 1, 2 (P = 0.011) and 1, 3 (P < 0.001) were found, but not between 2, 3 (P = 0.082). The MTR (in percent) of testicular carcinomas was 55.0 ± 3.2, significantly higher than that of benign lesions (50.3 ± 4.0, P = 0.02) and of normal testes (47.4 ± 2.2, P < 0.001).

conclusionsMTR of normal testes decreases with age. MTR might be helpful in the diagnostic work-up of testicular lesions. KEY POINTS: MTR of normal testes shows age-related changes. Testicular carcinomas have high MTR values. MTR may be useful in the diagnostic work-up of testicular lesions.

Indexed as

AdultAgedAged, 80 and overAge FactorsCohort StudiesEpididymitisFeasibility StudiesHumansImaging, Three-DimensionalMagnetic Resonance ImagingMaleMiddle AgedNeoplasms, Germ Cell and EmbryonalOrchitisTesticular DiseasesTesticular NeoplasmsGerm cellsMagnetic resonance imagingMagnetization transfer contrast imagingTestesTesticular neoplasms

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.