Evidence map›Paper›PMID 26065011›Full record

ArticleReceptors & clinical investigation

Prostate cancer metastatic to bone has higher expression of the calcium-sensing receptor (CaSR) than primary prostate cancer.

Jie Feng, Xiaojun Xu, Bo Li, Edward Brown, Alton B Farris, Shi-Yong Sun, Jenny J Yang

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Receptors & clinical investigation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Design of Calcium-Binding Proteins to Sense Calcium.Molecules (Basel, Switzerland) · 2020
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jie FengDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30303.
Xiaojun XuDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30303.
Bo LiDepartment of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA 30322.
Edward BrownDivision of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115.
Alton B FarrisDepartment of Pathology, Emory University, Atlanta, GA 30322.
Shi-Yong SunDepartment of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA 30322.
Jenny J YangDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30303.
Georgia State University · US

Funding

Structural Biology of receptor-mediated extracellular calcium signalingR01GM081749 · NIGMS · GEORGIA STATE UNIVERSITY · PI YANG, JENNY J. · 2007 to 2011
$1.2M
NIGMS NIH HHS R01 GM081749
6 · The paper itself

Abstract

The calcium-sensing receptor (CaSR) is the principal regulator of the secretion of parathyroid hormone and plays key roles in extracellular calcium (Ca

Indexed as

bonecalcium-sensing receptorcancermetastasisprostate

Identifiers

PMID26065011
PMCPMC4459757
OpenAlexW2146454333

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.