Evidence map›Paper›PMID 26064935›Full record

ReviewBioMed research international2015

Zebrafish as a Model for the Study of Human Myeloid Malignancies.

Jeng-Wei Lu, Meng-Shan Hsieh, Heng-An Liao, Yi-Ju Yang, Yi-Jung Ho, Liang-In Lin

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Zebrafish as a Model for Translational Immuno-Oncology.Journal of personalized medicine · 2025
    Review
  3. Article
  4. Zebrafish Xenograft Model to Study Human Cancer.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  5. Article
  6. Review
  7. Article
  8. Inducible Intestine-Specific Expression of krasNeoplasia (New York, N.Y.) · 2018
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jeng-Wei LuDepartment of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, No. 1 Chang-Te Street, Taipei 100, Taiwan.
Meng-Shan HsiehDepartment of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, No. 1 Chang-Te Street, Taipei 100, Taiwan.
Heng-An LiaoDepartment of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, No. 1 Chang-Te Street, Taipei 100, Taiwan.
Yi-Ju YangDepartment of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, No. 1 Chang-Te Street, Taipei 100, Taiwan.
Yi-Jung HoInstitute of Preventive Medicine, National Defense Medical Center, No. 172 Dapu Road, New Taipei City 237, Taiwan ; Graduate Institute of Life Sciences, National Defense Medical Center, No. 161, Section 6, Minquan East Road, Taipei 114, Taiwan.
Liang-In LinDepartment of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, No. 1 Chang-Te Street, Taipei 100, Taiwan ; Department of Laboratory Medicine, National Taiwan University Hospital, No. 7 Chung-Shan Southern Road, Taipei 100, Taiwan.
National Taiwan University · TWNational Defense Medical Center · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myeloid malignancies are heterogeneous disorders characterized by uncontrolled proliferation or/and blockage of differentiation of myeloid progenitor cells. Although a substantial number of gene alterations have been identified, the mechanism by which these abnormalities interact has yet to be elucidated. Over the past decades, zebrafish have become an important model organism, especially in biomedical research. Several zebrafish models have been developed to recapitulate the characteristics of specific myeloid malignancies that provide novel insight into the pathogenesis of these diseases and allow the evaluation of novel small molecule drugs. This report will focus on illustrative examples of applications of zebrafish models, including transgenesis, zebrafish xenograft models, and cell transplantation approaches, to the study of human myeloid malignancies.

Indexed as

Disease Models, AnimalAnimalsAnimals, Genetically ModifiedHumansLeukemia, MyeloidXenograft Model Antitumor AssaysZebrafish

Identifiers

PMID26064935
PMCPMC4433643
OpenAlexW1990682551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.