ArticleClinical endoscopy2015
Diagnostic Accuracy of the Initial Endoscopy for Ampullary Tumors.
Article in Clinical endoscopy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Therapeutic strategies and outcomes in the management of ampullary tumours: meta-analysis.BJS open · 2026Pooled it
- The Brescia International Multidisciplinary Consensus Guidelines on the Optimal Pathology Assessment and Multidisciplinary Pathways of Non-Pancreatic Neoplasms in and Around the Ampulla of Vater (PERIPAN).United European gastroenterology journal · 2025Guideline
- Article
- Extrahepatic biliary obstruction due to ampullary carcinoma in a dog.The Journal of veterinary medical science · 2026Article
- AI-assisted improvement of endoscopic diagnosis of ampullary lesions.NPJ digital medicine · 2026Article
- AI-powered hierarchical classification of ampullary neoplasms: a deep learning approach using white-light and narrow-band imaging.Surgical endoscopy · 2026Article
- [Overview of Nonmalignant Ampulla of Vater Neoplasms].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025Review
- [Diagnostic Work-up and Evaluation of Nonmalignant Ampullary Neoplasms].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025Review
- Endoscopic Management of Ampullary Adenomas: A Comprehensive Review.Journal of clinical medicine · 2025Review
- Article
- When thoracic trauma does more good than harm: About an incidental finding of a gangliocytic paraganglioma of the ampulla of Vater.Clinical case reports · 2024Article
- The Optimal Cutoff Value of Tumor Markers for Prognosis Prediction in Ampullary Cancer.Cancers · 2023Article
- Adenomatous neoplasia in the papilla of Vater endoscopic and/or surgical resection?Surgical endoscopy · 2022Article
- Efficacy and Safety of Exploring Deeper Sections of the Infrapapillary Area of the Duodenum by Using Sedative Esophagogastroduodenoscopy.Gastroenterology research and practice · 2022Article
- Surgical ampullectomy: A comprehensive review.World journal of gastrointestinal surgery · 2021Review
- Ampullary Adenocarcinoma: a Mini-Review and a Case Report of a Clinically Stable Disease Patient Treated with Herbal Supplements.Journal of gastrointestinal cancer · 2021Article
- Signet-ring cell carcinoma of the ampulla of Vater: a case diagnosed via repeated biopsies.Clinical journal of gastroenterology · 2020Article
- New experience of endoscopic papillectomy for ampullary neoplasms.Surgical endoscopy · 2019Article
- Differentiation of benign and malignant ampullary obstruction by multi-row detector CT.Japanese journal of radiology · 2018Article
- How to Improve Diagnostic Accuracy in Suspicious Ampullary Lesions?Clinical endoscopy · 2015Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsAmpullary tumors come in a wide variety of malignant forms. We evaluated the diagnostic accuracy of endoscopy for ampullary tumors, and analyzed the causes of misdiagnosis.
methodsWe compared endoscopic imaging and biopsy results to final diagnoses. Types of endoscope, numbers of biopsy specimens taken, and final diagnoses were evaluated as possible factors influencing diagnostic accuracy.
resultsFinal diagnoses were 19 adenocarcinomas, 18 normal or papillitis, 11 adenomas, two adenomyomas, one paraganglioma, and one neuroendocrine tumor. The diagnostic accuracy of endoscopic imaging or the initial biopsy was identical (67.3%). At least one test was concordant with the final diagnosis in all except two cases. Compared with the final diagnosis, endoscopic imaging tended to show more advanced tumors, whereas the initial biopsy revealed less advanced lesions. The diagnostic accuracy of the initial biopsy was influenced by the type of endoscope used and the final diagnosis, but not by the number of biopsies taken.
conclusionsEndoscopy has limited accuracy in the diagnosis of ampullary tumors. However, most cases with concordant endoscopic imaging and biopsy results are identical to the final diagnosis. Therefore, in cases where both of these tests disagree, re-evaluation with a side-viewing endoscope after resolution of papillitis is required.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.