ArticleInternational journal of clinical and experimental medicine2015
Association of β2-microglobulin with the prognosis of non-Hodgkin's lymphoma: a meta analysis.
Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Dynamic changes in serum IL-6, TNF-Frontiers in medicine · 2026Article
- Low Serum Beta-2 Microglobulin Level: A Possible Biomarker for Sarcopenia in the Elderly Population.Medicina (Kaunas, Lithuania) · 2024Article
- B-NHL Cases in a Tertiary Pediatric Hematology-Oncology Department: A 20-Year Retrospective Cohort Study.Life (Basel, Switzerland) · 2024Article
- Beta2-microglobulin is a valuable marker and identifies a poor-prognosis subgroup among intermediate-risk patients with diffuse large B cell lymphoma.Clinical and experimental medicine · 2023Article
- BaselineEJNMMI research · 2023Article
- A new nomogram for assessing complete response (CR) in gastric diffuse large B-cell lymphoma (DLBCL) patients after chemotherapy.Journal of cancer research and clinical oncology · 2023Article
- Primary lacrimal sac lymphoma: a case-based retrospective study in a Chinese population.International journal of ophthalmology · 2023Article
- Clinicopathologic study of mantle cell lymphoma with epstein-barr virus infection: A case series and literature review.Frontiers in oncology · 2022Article
- Nomograms based on SUVmax ofCancer imaging : the official publication of the International Cancer Imaging Society · 2021Article
- Prognostic factors of patients with mycosis fungoides.Postepy dermatologii i alergologii · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe influence of β2-microglobulin (β2-MG) on the prognosis of non-Hodgkin's lymphoma (NHL) remains controversial. This study performed meta-analyses to evaluate the prognostic value of β2-MG on the overall survival (OS) of NHL.
methodsThrough a search of relevant literature in PubMed, EMbase, Science Direct, OVID and Wanfang databases from 1980-2013, the hazard ratios (HRs) of OS between the normal β2-MG group and the increased β2-MG group were retrieved, and the results were combined using a fixed effect model and a random effect model. Subgroup analyses were performed based on univariate and multivariate analysis results, and sensitivity analyses were performed to estimate the changes of the combined HRs. In addition, funnel plots and fail-safe numbers were used to estimate publication bias.
resultsA total of 17 qualified publications were included, with a cumulative total of 2,479 cases. The result of heterogeneity examination showed that there was heterogeneity among all studies (P < 0.001, I(2) = 87%). In the random effect model, the combined HR was 2.71 (95% confidence interval [CI]: 1.91-3.85). The result of the total effect examination was statistically significant (Z = 5.59, P < 0.001).
conclusionThe increased β2-MG level was an independent risk factor for the prognosis of NHL.
Indexed as
Identifiers
26064301PMC4443135What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.