Evidence map›Paper›PMID 26064125›Full record

ArticleCase reports in medicine2015

Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature.

Guido Granata, Dario Didona, Giuseppina Stifano, Aldo Feola, Massimo Granata

Open access · goldAbstract read
In one paragraph

Article in Case reports in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
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  5. The History of Macrophage Activation Syndrome in Autoimmune Diseases.Advances in experimental medicine and biology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Guido GranataUOC Immunologia Clinica A, Dipartimento di Medicina Clinica, Policlinico Umberto I, Sapienza Università di Roma, 00185 Roma, Italy.
Dario DidonaI Divisione Dermatologica, Istituto Dermopatico dell'Immacolata IRCCS, 00167 Roma, Italy.
Giuseppina StifanoUOC Immunologia Clinica A, Dipartimento di Medicina Clinica, Policlinico Umberto I, Sapienza Università di Roma, 00185 Roma, Italy.
Aldo FeolaUOC Immunologia Clinica A, Dipartimento di Medicina Clinica, Policlinico Umberto I, Sapienza Università di Roma, 00185 Roma, Italy.
Massimo GranataUOC Immunologia Clinica A, Dipartimento di Medicina Clinica, Policlinico Umberto I, Sapienza Università di Roma, 00185 Roma, Italy.
Policlinico Umberto I · ITIstituto Dermopatico dell'Immacolata · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macrophage activation syndrome (MAS) is a potentially fatal condition. It belongs to the hemophagocytic lymphohistiocytosis group of diseases. In adults, MAS is rarely associated with systemic lupus erythematosus, but it also arises as complication of several systemic autoimmune disorders, like ankylosing spondylitis, rheumatoid arthritis, and adult-onset Still's disease. Several treatment options for MAS have been reported in the literature, including a therapeutic regimen of etoposide, dexamethasone, and cyclosporine. Here we report a case of 42-year-old woman in whom MAS occurred as onset of systemic lupus erythematosus.

Identifiers

PMID26064125
PMCPMC4439481
OpenAlexW1515437504

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.