ArticleNeuropsychiatric disease and treatment2015
Predictors of quality of life among individuals with schizophrenia.
Article in Neuropsychiatric disease and treatment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Conceptualisation of Mental Health Recovery by Health Professionals and Students in Southeast Asia: A Qualitative Systematic Review and Meta-Aggregation.Journal of psychiatric and mental health nursing · 2025Pooled it
- Development of the Japanese version of the Manchester short assessment of quality of life (MANSA) among people with self-reported severe mental illness.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Association of Depressive and Negative Symptoms with Quality of Life in Schizophrenia: A Cross-Sectional Inpatient Study.Journal of clinical medicine · 2026Article
- Self-stigma and suicide risk mediates the associations of inattention/impulsivity symptoms with psychological distress and quality of life among people with schizophrenia.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Predictors for quality of life improvement in schizophrenia: a prospective study of patients in hospital-based rehabilitation programs.BMC psychiatry · 2026Article
- Effect of cariprazine on attention and quality of life in patients with predominant negative symptoms of schizophrenia: A post-hoc analysis.Schizophrenia research. Cognition · 2025Article
- Health related quality of life among people with mental illness: The role of socio-clinical characteristics and level of functional disability.Frontiers in public health · 2023Article
- Mediators of quality of life change in people with severe psychotic disorders treated in integrated care: ACCESS II study.European psychiatry : the journal of the Association of European Psychiatrists · 2022Article
- Duration of the untreated period affects bone mineral density in psychiatric patients requiring long-term hospitalization: A cross-sectional study.PCN reports : psychiatry and clinical neurosciences · 2022Article
- Prediction of quality of life in schizophrenia using machine learning models on data from Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia trial.Schizophrenia (Heidelberg, Germany) · 2022Article
- Cariprazine, A Broad-Spectrum Antipsychotic for the Treatment of Schizophrenia: Pharmacology, Efficacy, and Safety.Advances in therapy · 2021Review
- Negative Symptoms of Schizophrenia: New Prospects of Cariprazine Treatment.Consortium psychiatricum · 2020Review
- Comparative assessment of quality of life of patients with schizophrenia attending a community psychiatric centre and a psychiatric hospital.Ghana medical journal · 2019Article
- Determinants of Health-Related Quality of Life in Schizophrenia: Beyond the Medical Model.Frontiers in psychiatry · 2018Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe study reported here aimed to evaluate both biological and psychosocial factors as predictors for quality of life as well as to examine the associations between the factors and quality of life in individuals with schizophrenia.
methodsEighty individuals with schizophrenia were recruited to the study. The Thai version of the World Health Organization Quality of Life-BREF was utilized to measure the quality of life. The five Marder subscales of the Positive and Negative Syndrome Scale were applied. Other tools for measurement included the Calgary Depression Scale for Schizophrenia and six social support deficits (SSDs). Pearson/Spearman correlation coefficients and the independent t-test were used for the statistical analysis to determine the associations of variables and the overall quality of life and the four domain scores. A multiple linear regression analysis of the overall quality of life and four domain scores was applied to determine their predictors.
resultsThe Positive and Negative Syndrome Scale total score, positive symptoms, negative symptoms, disorganized thought, and anxiety/depression showed a significant correlation with the overall quality of life and most of the four domain scores. Depression, SSDs, and adverse drug events showed a significant correlation with a poorer overall quality of life. The multiple linear regression model revealed that negative symptoms, depression, and seeing a relative less often than once per week were predictors for the overall quality of life (adjusted R (2)=0.472). Negative symptoms were also found to be the main factors predicting a decrease in the four domains of quality of life - physical health, psychological, social relationships, and environment.
conclusionNegative symptoms, depression, and poor contact with relatives were the foremost predictors of poor quality of life in individuals with schizophrenia. Positive symptoms, negative symptoms, disorganized thought, anxiety/depression, SSDs, and adverse events were also found to be correlated with quality of life.
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