ArticleDisease markers2015
Vitamin D Is a Good Marker for Disease Activity of Rheumatoid Arthritis Disease.
Article in Disease markers, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- The Association between Vitamin D and Peripheral Arterial Disease and its Value as a Prognostic and Diagnostic Marker A Systematic Review and Meta-Analysis.Current atherosclerosis reports · 2025Pooled it
- Serum Vitamin D Level and Rheumatoid Arthritis Disease Activity: Review and Meta-Analysis.PloS one · 2016Pooled it
- Contributions of Dietary Patterns and Factors to Regulation of Rheumatoid Disease.International journal of molecular sciences · 2025Review
- Seasonal and Treatment-Related Variation in 25-Hydroxy Vitamin D Concentration in Patients with Rheumatoid Arthritis.Journal of clinical medicine · 2024Article
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- Vitamin D Levels Among Rheumatoid Arthritis Sudanese Patients: Prevalence and Correlation to Disease Activity - A Bicentric Study.Open access rheumatology : research and reviews · 2023Article
- Vitamin D deficiency: concern for rheumatoid arthritis and COVID-19?Molecular and cellular biochemistry · 2021Review
- IL-38 and IL-36 Target Autophagy for Regulating Synoviocyte Proliferation, Migration, and Invasion in Rheumatoid Arthritis.Disease markers · 2021Article
- Vitamin D, autoimmunity and immune-related adverse events of immune checkpoint inhibitors.Archives of dermatological research · 2021Review
- Vitamin D as a Principal Factor in Mediating Rheumatoid Arthritis-Derived Immune Response.BioMed research international · 2019Review
- Effect of Vitamin D and Calcium Supplementation in Patients with Systemic Lupus Erythematosus.Saudi journal of medicine & medical sciencesArticle
- Assessment of Vitamin D in Rheumatoid Arthritis and Its Correlation with Disease Activity.Journal of natural science, biology, and medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThis study was conducted to find out the optimal vitamin D cutoff point in predicting activity of RA disease. MATERIALS AND
methodsOne hundred and two rheumatoid arthritis Saudi patients of both genders were recruited in this study. Vitamin D as 25-hydroxy-vitamin D [25(OH)D] was measured and serum level less than 20 ng/mL defined as deficient patient. Disease activity was measured based on the disease activity score index of a 28-joint count (DAS28) using serum erythrocyte sedimentation rate levels. Receiver operating characteristic (ROC) curves were used to determine the optimal vitamin D cutoff points for identifying disease activity.
resultsIt has been observed that vitamin D levels were lower (P < 0.05) in patients with high disease activity. A significant inverse correlation between serum 25(OH)D levels and DAS28 (r = -0.277, P = 0.014) was shown. ROC curves results showed that vitamin D less than 12.3 ng/mL predicted high disease activity, and vitamin D more than 17.9 ng/mL predicted low disease activity, with good sensitivity and accuracy results regarding vitamin D.
conclusionStudy results concluded that vitamin D is a good predictor of RA disease activity in Saudi patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.