Evidence map›Paper›PMID 26063693›Full record

Trial reportThe American journal of clinical nutrition2015

Dietary Approaches to Stop Hypertension diet retains effectiveness to reduce blood pressure when lean pork is substituted for chicken and fish as the predominant source of protein.

R Drew Sayer, Amy J Wright, Ningning Chen, Wayne W Campbell

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in The American journal of clinical nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

R Drew SayerDepartments of Nutrition Science and.
Amy J WrightDepartments of Nutrition Science and.
Ningning ChenStatistics, Purdue University, West Lafayette, IN.
Wayne W CampbellDepartments of Nutrition Science and campbellw@purdue.edu.

Funding

Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
NCATS NIH HHS UL1 TR001108NCATS NIH HHS UL1TR001108
6 · The paper itself

Abstract

backgroundHypertension is a major, modifiable risk factor for cardiovascular and kidney disease and premature mortality that is improved by the DASH (Dietary Approaches to Stop Hypertension) diet. The DASH diet emphasizes increased consumption of fruit and vegetables, whole grains, low-fat dairy, nuts, and poultry and fish and reduced intakes of fats, red meats (including pork), sodium, and added sugars.

objectiveWe sought to evaluate whether the consumption of lean pork compared with the consumption of chicken and fish as the predominant protein source in a DASH-style diet affected blood pressure (BP) control in men and women with elevated BP.

designIn a randomized crossover study, 13 women and 6 men [mean ± SEM age: 61 ± 2 y; BMI (in kg/m²): 31.2 ± 1.4] with elevated BP [systolic blood pressure (SBP)/diastolic blood pressure (DBP): 130 ± 2/85 ± 2 mm Hg] consumed a DASH-style diet for two 6-wk controlled dietary interventions (with a 4-wk diet washout between interventions) with either lean pork [DASH diet with pork (DASH-P)] or chicken and fish [DASH diet with chicken and fish (DASH-CF), the control diet] as the major protein source (55% of total protein intake). SBP and DBP were measured manually and with a 24-h BP monitoring system on 3 d before and 3 d at the end of each diet intervention.

resultsPreintervention manual BP (DASH-P: 130/84 ± 2/1 mm Hg; DASH-CF: 129/84 ± 2/1 mg Hg) and postintervention manual BP (DASH-P: 122/79 ± 2/1 mm Hg; DASH-CF: 123/78 ± 3/1) were not different between the DASH-P and DASH-CF. Consumption of these DASH-style diets for 6 wk reduced all measures of BP (P < 0.05) with no differences in responses between the DASH-CF and DASH-P.

conclusionThe results indicate that adults with elevated BP may effectively incorporate lean pork into a DASH-style diet for BP reduction.

Indexed as

Diet, Fat-RestrictedDiet, Sodium-RestrictedSus scrofaAnimalsBody Mass IndexChickensCross-Over StudiesDiet, Carbohydrate-RestrictedFemaleFishesHumansHypertensionIndianaIntention to Treat AnalysisMaleMeatblood pressureDASH dietfishporkpoultryprotein sourcered meat

Identifiers

PMID26063693
PMCPMC4515871

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.