ArticleParasites & vectors2015
Epidemiology of coinfection with soil transmitted helminths and Plasmodium falciparum among school children in Bumula District in western Kenya.
Article in Parasites & vectors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 5 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 5 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Prevalence and effect of Plasmodium spp. and hookworm co-infection on malaria parasite density and haemoglobin level: a meta-analysis.Scientific reports · 2022Pooled it
- Malaria and helminth co-infections in children living in endemic countries: A systematic review with meta-analysis.PLoS neglected tropical diseases · 2021Pooled it
- The extent, nature, and pathogenic consequences of helminth polyparasitism in humans: A meta-analysis.PLoS neglected tropical diseases · 2019Pooled it
- Prevalence and distribution of soil-transmitted helminth infections in Nigerian children: a systematic review and meta-analysis.Infectious diseases of poverty · 2018Pooled it
- Plasmodium and intestinal parasite perturbations of the infected host's inflammatory responses: a systematic review.Parasites & vectors · 2018Pooled it
- Soil-Transmitted Helminthes (STHs) and Asymptomatic Bacteriuria Amongst Preschool Children in the Bosomtwe District of Ghana.BioMed research international · 2026Article
- Experimental evolution of Plasmodium yoelii in single and helminth-coinfected mice.Malaria journal · 2025Article
- Precision mapping of schistosomiasis and soil-transmitted helminthiasis among school-age children: Targeting interventions in western Kenya.PLoS neglected tropical diseases · 2025Article
- Two-photon NAD(P)H-FLIM reveals unperturbed energy metabolism of Ascaris suum larvae, in contrast to host macrophages upon artemisinin derivatives exposure.Scientific reports · 2025Article
- Prevalence of Plasmodium and Soil-Transmitted Helminth Coinfection and Associated Factors among Malaria-Suspected Patients Attending Shewa Robit Health Center, North-Central Ethiopia.The American journal of tropical medicine and hygiene · 2024Article
- Factors influencing stunted growth in children: A study in Bandung regency focusing on a deworming program.Parasite epidemiology and control · 2024Article
- Assessment of the selected hematological profiles among malaria andJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024Article
- Article
- Factors associated with anemia among children in South and Southeast Asia: a multilevel analysis.BMC public health · 2023Article
- Infection with soil-transmitted helminths and their impact on coinfections.Frontiers in parasitology · 2023Review
- Prevalence of malaria-helminth co-infections among children living in a setting of high coverage of standard interventions for malaria and helminths: Two population-based studies in Senegal.Frontiers in public health · 2023Article
- Prevalence and Determinants of Geohelminthiasis among School-Age Children in Jimma City, Ethiopia.Journal of tropical medicine · 2023Article
- Prevalence and distribution pattern of malaria and soil-transmitted helminth co-endemicity in sub-Saharan Africa, 2000-2018: A geospatial analysis.PLoS neglected tropical diseases · 2022Article
- Prevalence of Soil-Transmitted Helminthes and Associated Risk Factors Among People of Ethiopia: A Systematic Review and Meta-Analysis.Infectious diseases · 2022Article
- Anemia among Schoolchildren with Malaria and Soil-Transmitted Helminth Coinfections after Repeated Rounds of Mass Drug Administration in Muheza District, Tanzania.The American journal of tropical medicine and hygiene · 2019Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundMany school children living in Africa are infected with plasmodia and helminth species and are consequently at risk of coinfection. However, the epidemiology of such coinfection and the implications of coinfection for children's health remain poorly understood. This study describes the epidemiology of Ascaris lumbricoides-Plasmodium and hookworm-Plasmodium coinfection among school children living in western Kenya and investigates the associated risk factors.
methodsAs part of a randomized trial, a baseline cross-sectional survey was conducted among school children aged 5-18 years in 23 schools in Bumula District. Single stool samples were collected to screen for helminth infections using the Kato-Katz technique and malaria parasitaemia was determined from a finger prick blood sample. Demographic and anthropometric data were also collected.
resultsOverall, 46.4% of the children were infected with Plasmodium falciparum while 27.6% of the children were infected with at least one soil transmitted helminth (STH) species, with hookworm being the most common (16.8%) followed by A. lumbricoides (15.3%). Overall 14.3% of the children had STH-Plasmodium coinfection, with hookworm-Plasmodium (9.0%) coinfection being the most common. Geographical variation in the prevalence of coinfection occurred between schools. In multivariable logistic regression analysis, hookworm was positively associated with P. falciparum infection. In stratified analysis, hookworm infection was associated with increased odds of P. falciparum infection among both boys (P < 0.001) and girls (P = 0.01), whereas there was no association between A. lumbricoides and P. falciparum.
conclusionThese findings demonstrate STH infections are still prevalent, despite the ongoing national deworming programme in Kenya, and that malaria parasitaemia is widespread, such that coinfection occurs among a proportion of children. A subsequent trial will allow us to investigate the implications of coinfection for the risk of clinical malaria.
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