Observational studyReproductive health2015
Neonatal mortality and coverage of essential newborn interventions 2010 - 2013: a prospective, population-based study from low-middle income countries.
Observational study in Reproductive health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01073475 (Global Network for Women's and Children's Health Research Maternal Newborn Health Registry), which is not on this map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Global Network for Women's and Children's Health Research Maternal Newborn Health Registry
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Creation of a Weight of Evidence Scoring Database for Risk Factors for Adverse Impacts to Birth Outcomes Using Expert Elicitation.Birth defects research · 2026Pooled it
- A machine learning approach to identify key socio-economic and demographic factors associated with neonatal mortality in Ethiopia.BMC public health · 2026Article
- Time to Death and Predictors of Mortality in Neonates Admitted to Tibebe Ghion Referral Hospital, Neonatal Intensive Care Unit in Northwest Ethiopia: A Retrospective Follow-Up Study.Health science reports · 2026Article
- The effectiveness of using simulation in undergraduate medical students' training in neonatal resuscitation.Sudanese journal of paediatrics · 2026Article
- Mortality Projections, Regional Disparities in the Burden of Neonatal Disorders, and the Status of Achieving SDG Targets by 2030 in South Asia: Insights from the Global Burden of Disease Study 2021.Journal of epidemiology and global health · 2025Article
- The Trend in Delayed Childbearing Age and Its Potential Impact on Adverse Maternal-Perinatal Outcomes in Developed and Developing Countries: A Narrative Review.Iranian journal of public health · 2025Review
- Nutritional status of Vietnamese infants assessed by Fenton growth chart and related factors: A cross-sectional study.Pediatric investigation · 2023Article
- Why Babies die in the first 7 days after birth in Somalia Region of Ethiopia?Annals of medicine and surgery (2012) · 2023Article
- Epidemiology of neonatal mortality: a spatial and multilevel analysis of the 2019 mini-Ethiopian demographic and health survey data.BMC pediatrics · 2023Article
- Neonatal Mortality at Felege Hiwot Comprehensive Specialized Hospital in Ethiopia Over 5 years: Trends and Associated Factors.Clinical medicine insights. Pediatrics · 2023Article
- 2.5 Million Annual Deaths-Are Neonates in Low- and Middle-Income Countries Too Small to Be Seen? A Bottom-Up Overview on Neonatal Morbi-Mortality.Tropical medicine and infectious disease · 2022Review
- Exploring the lived experiences of parents caring for infants with gastroschisis in Rwanda: The untold story.PLOS global public health · 2022Article
- Article
- Overnight admissions to a neonatal intensive care unit in Ethiopia are not associated with increased mortality.PloS one · 2022Article
- Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study.Lancet (London, England) · 2021Article
- Maternal and neonatal data collection systems in low- and middle-income countries for maternal vaccines active safety surveillance systems: A scoping review.BMC pregnancy and childbirth · 2021Article
- A 12 Years Neonatal Mortality Rate and Its Predictors in Eastern Ethiopia.Global pediatric health · 2021Article
- Article
- Risk Factors for Neonatal Mortality in Preterm Newborns in The Extreme South of Brazil.Scientific reports · 2020Article
- Adverse pregnancy outcomes among women presenting at antenatal clinics in Ouélessébougou, Mali.Reproductive health · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Funding
Abstract
backgroundApproximately 3 million neonatal deaths occur each year worldwide. Simple interventions have been tested and found to be effective in reducing the neonatal mortality. In order to effectively implement public health interventions, it is important to know the rates of neonatal mortality and understand the contributing risk factors. Hence, this prospective, population-based, observational study was carried out to inform these needs.
methodsThe Global Network's Maternal Newborn Health Registry was initiated in the seven sites in 2008. Registry administrators (RAs) attempt to identify and enroll all eligible women by 20 weeks gestation and collect basic health data, and outcomes after delivery and at 6 weeks post-partum. All study data were collected, reviewed, and edited by staff at each study site. The study was reviewed and approved by each sites' ethics review committee.
resultsOverall, the 7-day neonatal mortality rate (NMR) was 20.6 per 1000 live births and the 28-day NMR was 25.7 per 1000 live births. Higher neonatal mortality was associated with maternal age > 35 and <20 years relative to women 20-35 years of age. Preterm births were at increased risk of both early and 28-day neonatal mortality (RR 8.1, 95% CI 7.5-8.8 and 7.5, 95% CI 6.9-8.1) compared to term as were those with low birth weight (<2500g). Neonatal resuscitation rates were 4.8% for hospital deliveries compared to 0.9% for home births. In the hospital, 26.5% of deliveries were by cesarean section with an overall cesarean section rate of 12.5%. Neonatal mortality rates were highest in the Pakistan site and lowest in Argentina.
conclusionsUsing prospectively collected data with high follow up rates (99%), we documented characteristics associated with neonatal mortality. Low birth weight and prematurity are among the strongest predictors of neonatal mortality. Other risk factors for neonatal deaths included male gender, multiple gestation and major congenital anomalies. Breech presentation/transverse lie, and no antenatal care were also significant risk factors for neonatal death. Coverage of interventions varied by setting of delivery, with the overall population rate of most evidence-based interventions low. This study informs about risk factors for neonatal mortality which can serve to design strategies/interventions to reduce risk of neonatal mortality.
trial registrationThe trial is registered at clinicaltrials.gov. ClinicalTrial.gov
trial registrationNCT01073475.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.